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Cyclamate Structure

Cyclamate

Chemical Properties

Melting point >300 °C (lit.)
Density  1.58[at 20℃]
vapor pressure  0.002Pa at 150℃
storage temp.  room temp
solubility  200g/l
form  Powder
color  White
Odor Odorless. Sweet taste, perceptible at concentrations higher than 100 ppm in water.
PH 5.5-7.5 (100g/l, H2O, 20℃)
Water Solubility  >=10 g/100 mL at 20 ºC
Merck  14,2703
BRN  4166868
Stability Hygroscopic
InChIKey UDIPTWFVPPPURJ-UHFFFAOYSA-M
LogP -2.63 at 20℃
CAS DataBase Reference 139-05-9(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) SODIUM CYCLAMATE--PROHIBITED
EWG's Food Scores 1
FDA UNII 1I6F42RME1
IARC 3 (Vol. Sup 7, 73) 1999
EPA Substance Registry System Sodium cyclamate (139-05-9)

Safety

Symbol(GHS)
Signal wordWarning
Hazard statements H302
Precautionary statements P264-P270-P501-P301+P312a-P330-P501a-P301+P312+P330
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36/37-24/25
WGK Germany  3
RTECS  GV7350000
TSCA  Yes
HS Code  29299000
Toxicity Sodium cyclamate is a non-nutritive sweetener that is about 30 times sweeter than cane sugar. The oral LD50s in rats and mice are 15.25 and 17.0 g/kg, respectively. It was banned as a food additive because of findings that it caused bladder cancer in rodents. It appears to act as a promoter. There is also evidence that it causes toxicity in the male reproductive system.
NFPA 704:
0
2 0

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