Cyclosporine A
- Product NameCyclosporine A
- CAS59865-13-3
- CBNumberCB00128804
- MFC62H111N11O12
- MW1202.61
- EINECS611-907-1
- MDL NumberMFCD00274558
- MOL File59865-13-3.mol
- MSDS FileSDS
Chemical Properties
| Melting point | 148-151°C |
| Boiling point | 838.63°C (rough estimate) |
| alpha | D20 -244° (c = 0.6 in chloroform); D20 -189° (c = 0.5 in methanol) |
| Density | 0.9913 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| Flash point | 87℃ |
| storage temp. | -20°C |
| solubility | ethanol: 30 mg/mL |
| form | solid |
| pka | 13.32±0.70(Predicted) |
| color | white |
| optical activity | -18922 (methanol) |
| Water Solubility | Soluble in dimethyl sulfoxide and ethanol. Insoluble in water. |
| Merck | 14,2752 |
| BRN | 3647785 |
| Stability | Stable for 3 years as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
| InChIKey | PMATZTZNYRCHOR-CGLBZJNRSA-N |
| CAS DataBase Reference | 59865-13-3(CAS DataBase Reference) |
Safety
| Symbol(GHS) |
 
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| Signal word | Danger | |||||||||
| Hazard statements | H302-H350-H360FD | |||||||||
| Precautionary statements | P201-P202-P264-P270-P301+P312-P308+P313 | |||||||||
| Hazard Codes | T,Xn,F | |||||||||
| Risk Statements | 45-60-22-40-36-20/21/22-11 | |||||||||
| Safety Statements | 53-45-36/37-24/25-22-26-16 | |||||||||
| RIDADR | UN 1648 3 / PGII | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | GZ4120000 | |||||||||
| HS Code | 29419090 | |||||||||
| Hazardous Substances Data | 59865-13-3(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 in mice, rats, rabbits (mg/kg): 107, 25, >10 i.v.; 2329, 1480, >1000 orally (Ryffel) | |||||||||
| NFPA 704: |
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