Phosphatidylcholine

Description

Phosphatidylcholine (PC) is a phospholipid attached to a choline particle. Phospholipids contain fatty acids, glycerol, and phosphorous. The phosphorous part of the phospholipid substance — the lecithin — is made up of PC. For this reason, the terms phosphatidylcholine and lecithin are often used interchangeably, although they’re different. Foods that contain lecithin are the best dietary sources of PC. Although PC is traditionally used to support brain health, it can also support liver function and keep cholesterol levels in check.

Occurrence

Phosphatidylcholine is a chemical contained in eggs, soybeans, mustard, sunflower, and other foods. It is found naturally in the body in all cells. Phosphatidylcholine is also a source of choline in the body.

Side effects

Oral PC may cause excessive sweating, and taking more than 30 grams daily may cause:diarrhea, nausea, and vomiting.
Injecting PC directly into a fatty tumor may cause severe inflammation or fibrosis. It may also cause: pain, burning, itching, bruising, edema, and reddening of skin.
Taking PC with an AChE inhibitor, such as donepezil (Aricept) or tacrine (Cognex), may increase acetylcholine levels in the body. This may cause cholinergic side effects, including: seizures, muscle weakness, slow heartrate, and breathing problems.
Taking PC with cholinergic or anticholinergic drugs may also impact their effectiveness. PC has not been proven safe for women who are pregnant or breastfeeding, and it’s therefore not recommended.