Natriumchloracetat

Bezeichnung:Natriumchloracetat

CAS-Nr3926-62-3

Englisch Name:Sodium chloroacetate

CBNumberCB9853591

SummenformelC2H2ClNaO2

Molgewicht116.48

MOL-Datei3926-62-3.mol

Synonyma

Natriumchloracetat

Natriummonochloracetat

Chloressigs?ure, Natriumsalz

Natriumchloracetat physikalisch-chemischer Eigenschaften

Schmelzpunkt	199 °C (dec.)(lit.)
chüttdichte	850kg/m3
Dichte	1.87[at 20℃]
Dampfdruck	0.001Pa at 20℃
Brechungsindex	1.438
Flammpunkt	270°C
storage temp.	-20°C
Löslichkeit	820g/l
Aggregatzustand	Crystalline Powder
Farbe	White
PH	4.5-9.0 (50g/l, H2O, 20℃)
Biologische Quelle	mouse
Wasserlöslichkeit	440 g/L (20 ºC)
Sensitive	Hygroscopic
Merck	14,2112
BRN	3597157
Stabilität	Stable. Incompatible with strong oxidizing agents.
InChI	1S/C2H3ClO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1
InChIKey	FDRCDNZGSXJAFP-UHFFFAOYSA-M
SMILES	[Na+].[O-]C(=O)CCl
LogP	-3.8 at 20℃
CAS Datenbank	3926-62-3(CAS DataBase Reference)
EPA chemische Informationen	Sodium chloroacetate (3926-62-3)

Sicherheit

Kennzeichnung gefährlicher	T,N
R-Sätze:	25-38-50-36
S-Sätze:	22-37-45-61-26
RIDADR	UN 2659
WGK Germany	2
RTECS-Nr.	AG1400000
TSCA	TSCA listed
HazardClass	6.1
PackingGroup	III
HS Code	29154000
Speicherklasse	6.1D - Non-combustible acute toxic Cat.3 toxic hazardous materials or hazardous materials causing chronic effects
Hazard Classifications	Acute Tox. 3 Oral Aquatic Acute 1 Eye Irrit. 2 Skin Irrit. 2
Toxizität	LD50 orally in Rabbit: 95 mg/kg LD50 dermal Rat > 2000 mg/kg

Gefahreninformationscode (GHS)

Sodium chloroacetate Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD
FARBLOSE KRISTALLEODER WEISSES PULVER.
CHEMISCHE GEFAHREN
Beim Verbrennen Bildung giftiger und ätzender Rauche mit Chlor und Chlorwasserstoff.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK nicht festgelegt (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den Körper durch Verschlucken.
INHALATIONSGEFAHREN
Verdampfung bei 20°C vernachlässigbar; eine gesundheitsschädliche Partikelkonzentration in der Luft kann jedoch beim Versprühen schnell erreicht werden.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION:
Die Substanz reizt die Augen und die Atemwege. Möglich sind Auswirkungen auf Zentralnervensystemund Herz-Kreislaufsystem mit nachfolgenden Krämpfen, Herzfunktionsstörungenund Nierenschäden.
LECKAGE
NICHT in die Umwelt gelangen lassen. Verschüttetes Material in Behältern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern. Reste sorgfältig sammeln. An sicheren Ort bringen. Reste mit viel Wasser wegspülen. Persönliche Schutzausrüstung: Atemschutzgerät, P3-Filter für giftige Partikel.
R-Sätze Betriebsanweisung:
R25:Giftig beim Verschlucken.
R38:Reizt die Haut.
R50:Sehr giftig für Wasserorganismen.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S37:Geeignete Schutzhandschuhe tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Chemische Eigenschaften
Sodium chloroacetate is a white crystalline powder. It is soluble in water. It may be toxic ingestion or inhalation.
Sodium chloroacetate is a reactive and toxic material, so it is hydrolyzed to glycolic acid nearly quantitatively at the end of the production cycle. Chloroacetic acid always contains traces of dichloroacetic acid, a toxic and unreactive material that appears on the California Prop.65 list.
Verwenden
Sodium chloroacetate is used to prepare dyes and active pharmaceutical ingredients. It is also used as an odor agent, surface active agent and viscosity adjustor.
Verwenden
Sodium chloroacetate is the sodium salt of chloroacetic acid. It is used to prepare weed killers, dyes, vitamins and active pharmaceutical ingredients. It is also used as an odor agent, surface active agent and viscosity adjustor. Sodium dihydroxyethyltallow glycinate is the condensation product of dihydroxyethyl tallow amine and sodiumchloroacetate.It is used as a thickeningagent and asurfactant.
Vorbereitung Methode
Sodium monochloroacetate is commercially produced through a neutralisation reaction involving monochloroacetic acid and sodium hydroxide or sodium carbonate. This process typically takes place in a controlled reactor system where monochloroacetic acid is gradually added to an aqueous solution of the sodium base, maintaining precise temperature and pH conditions to ensure complete conversion and minimize side reactions. The resulting material is then purified, often via crystallization or filtration and dried.
Allgemeine Beschreibung
Chloroacetic acid sodium salt is a white colored powdered solid. Chloroacetic acid sodium salt is soluble in water.Chloroacetic acid sodium salt may be toxic ingestion or inhalation. Sodium chloroacetate is used as a contact herbicide and a component in other herbicides, an intermediate in the production of carboxymethyl-cellulose, and other synthetic organic chemicals.
Air & Water Reaktionen
Chloroacetic acid sodium salt is soluble in water.
Reaktivität anzeigen
Salts, basic, such as Chloroacetic acid sodium salt, are generally soluble in water. The resulting solutions contain moderate concentrations of hydroxide ions and have pH's greater than 7.0. They react as bases to neutralize acids. These neutralizations generate heat, but less or far less than is generated by neutralization of the bases in reactivity group 10 (Bases) and the neutralization of amines. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.
Health Hazard
Highly toxic, may be fatal if inhaled, swallowed or absorbed through skin. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Brandgefahr
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Containers may explode when heated. Runoff may pollute waterways.
Flammability and Explosibility
Non flammable
Biochem/physiol Actions
Actin plays an important role in cell motility, structure and integrity. Smooth muscle actin-α (SMA)/ α2-smooth muscle actin (ACTA2) interacts with β-myosin heavy chain and helps in vascular smooth muscle cell contraction. The encoded protein modulates the expression of c-MET (tyrosine-protein kinase Met) and focal adhesion kinase (FAK) in human lung adenocarcinoma cells, which positively and selectively mediates tumor progression. Mutation in the gene expression leads to thoracic aortic aneurysms and dissections (TAAD).
Mechanism of action
Thought to interfere with plant metabolism, leading to growth inhibition and eventual plant death.
Sicherheitsprofil
Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of Cland NazO. Used as an herbicide
Pestizidtyp
Herbicide

Sodium chloroacetate Upstream-Materialien And Downstream Produkte

Natriumchloracetat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

3926-62-3, Sodium chloroacetate Verwandte Suche:

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