(+)-L-Argininhydrochlorid

Bezeichnung:(+)-L-Argininhydrochlorid

CAS-Nr1119-34-2

Englisch Name:L-Arginine hydrochloride

CBNumberCB9700536

SummenformelC6H15ClN4O2

Molgewicht210.66

MOL-Datei1119-34-2.mol

Synonyma

(+)-L-Argininhydrochlorid

(+)-L-Argininhydrochlorid physikalisch-chemischer Eigenschaften

Schmelzpunkt	226-230 °C(lit.)
Siedepunkt	235℃[at 101 325 Pa]
alpha	22 º (c=8,6N HCl)
Dichte	1.42
Dampfdruck	<1 Pa (20 °C)
FEMA	3819 \| L-ARGININE
storage temp.	2-8°C
Löslichkeit	H₂O: 100 mg/mL
Aggregatzustand	powder
pka	1[at 20 ℃]
Farbe	white
Geruch (Odor)	odorless
Säure-Base-Indikators(pH-Indikatoren)	5.5 - 7
PH	5.5-7.0 (25℃, 1M in H2O)
Optische Aktivität	[α]20/D +22.0±0.5°, c = 5% in 5 M HCl
Wasserlöslichkeit	Soluble in water. Slightly soluble in hot alcohol.
Sensitive	Hygroscopic
maximale Wellenlänge (λmax)	λ: 260 nm Amax: ≤0.2 λ: 280 nm Amax: ≤0.1
Merck	14,780
BRN	3631658
Stabilität	Stable. Incompatible with strong oxidizing agents.
LogP	-8.5--3.24 at 25℃
CAS Datenbank	1119-34-2(CAS DataBase Reference)
EPA chemische Informationen	L-Arginine, monohydrochloride (1119-34-2)

Sicherheit

Kennzeichnung gefährlicher	Xi,Xn
R-Sätze:	37-36/38-36/37/38-20/21/22
S-Sätze:	37/39-26-24/25-36
WGK Germany	2
RTECS-Nr.	CF1995500
F	3-10
TSCA	Yes
HS Code	29252000
Toxizität	LD50 orally in Rabbit: 12000 mg/kg

Gefahreninformationscode (GHS)

L-Arginine hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R37:Reizt die Atmungsorgane.
R36/38:Reizt die Augen und die Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
L-Arginine hydrochloride is a salt form of L-Arginine, where hydrochloric acid is added to enhance stability and solubility. Arginine hydrochloride is a L-alpha-amino acid. An essential amino acid that is physiologically active in the L-form. L-Arginine might be effective at lowering blood pressure, reducing the symptoms of angina and PAD , and treating erectile dysfunction due to a physical cause.
Chemische Eigenschaften
White crystalline powder
Verwenden
An essential amino acid for human development. Precursor for nitric oxide. Ammonia detoxicant (hepatic failure); diagnostic aid (pituitary function).
Verwenden
gastric acid depressant
Verwenden
L-Arginine monohydrochloride is used in the treatment of heart and circulatory diseases. It is a precursor of nitric oxide synthesis that induces vasodilation in vivo, there by relaxing blood vessels. It is also used in the treatment of angina and other cardiovascular problems. It is an important intermediate in the urea cycle and involved in the detoxification of nitrogenous wastes. It is commonly used in cell culture media and drug development.
Definition
ChEBI: Arginine hydrochloride is a L-alpha-amino acid.
Trademarks
R-Gene 10 (Pharmacia & Upjohn).
Biochem/physiol Actions
L-Arginine is considered as a semi essential amino acid. In most mammals including humans, L-Arginine synthesis occurs through intestinal-renal axis, from glutamine, glutamate and proline. Abnormal levels of L-Arginine is associated with the development of kidney and cardiovascular disease. L-arginine is found to decrease fat mass and visceral adiposity.
Nebenwirkungen
L-arginine has some potential side effects to consider when taking it as a supplement. Some of the more common and benign side effects can include: nausea, diarrhea, bloating, and abdominal pain. However, L-arginine may result in some serious complications.
Sicherheitsprofil
Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. An experimental teratogen. When heated to decomposition it emits very toxic fumes of NOx and HCl.
läuterung methode
A likely impurity is ornithine. Crystallise the salt from H2O at pH 5-7, by adding EtOH to 80% (v/v). [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 1841 1961, Beilstein 4 IV 2649.]

L-Arginine hydrochloride Upstream-Materialien And Downstream Produkte

(+)-L-Argininhydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

1119-34-2, L-Arginine hydrochloride Verwandte Suche:

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