Sodium trifluoromethanesulfinate

Bezeichnung:Sodium trifluoromethanesulfinate

CAS-Nr2926-29-6

Englisch Name:Sodium trifluoromethanesulfinate

CBNumberCB9308440

SummenformelCH2F3NaO2S

Molgewicht158.07

MOL-Datei2926-29-6.mol

Sodium trifluoromethanesulfinate physikalisch-chemischer Eigenschaften

Schmelzpunkt	<325°C
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
Löslichkeit	Water (Sparingly)
Aggregatzustand	powder
Farbe	white
BRN	3723394
InChI	InChI=1S/CHF3O2S.Na.H/c2-1(3,4)7(5)6;;/h(H,5,6);;
InChIKey	KAVUKAXLXGRUCD-UHFFFAOYSA-M
SMILES	C(F)(F)(F)S(O)=O.[NaH]

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38-36/38
S-Sätze:	26-36/37/39
WGK Germany	3
TSCA	No
HazardClass	IRRITANT
HS Code	29309090
Speicherklasse	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2

Gefahreninformationscode (GHS)

Sodium trifluoromethanesulfinate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
White to light yellow solid
Verwenden
Sodium Triflinate (Sodium trifluoromethanesulfinate), is a sulfur-containing building block and Fluorination reagents, used in various organic synthesis. It can be used in a new and convenient method for the copper-catalyzed construction of functional sulfonamides in good yields and excellent chemoselectivity.
Verwenden
Efficient sulfinate salt for the trifluoromethylation of various aryls, aryl boronic acids, alkenes, and alkynes.
reaction suitability
reaction type: C-C Bond Formation
Solubility in water
soluble in H2O, slightly soluble in MeOH, MeCN, and acetone.
Synthese
At first, an aqueous solution was prepared by dissolving 37.5 g of sodium sulfite in 150 g of water. Then, a metal pressure-proof reactor was charged with this aqueous solution. After that, the atmosphere of the reactor was removed to obtain a reduced pressure. 10.7 g of trifluoromethanesulfonic fluoride was added to the reactor, stirring at 5° C. for 4 hr. The resulting reaction liquid was neutralized with sodium carbonate, followed by water removal. Then, methanol was added to the remaining solid matter to extract the target product. The resulting methanol solution was concentrated to dryness, thereby obtaining 9.7 g of sodium trifluoromethanesulfinate (yield: 88%).
Einzelnachweise
[1] Patent: US2001/31891, 2001, A1

Sodium trifluoromethanesulfinate Upstream-Materialien And Downstream Produkte

Sodium trifluoromethanesulfinate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

2926-29-6, Sodium trifluoromethanesulfinate Verwandte Suche:

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