1,4-Diisothiocyanatobenzol

Bezeichnung:1,4-Diisothiocyanatobenzol

CAS-Nr4044-65-9

Englisch Name:1,4-PHENYLENE DIISOTHIOCYANATE

CBNumberCB5292882

SummenformelC8H4N2S2

Molgewicht192.26

MOL-Datei4044-65-9.mol

Synonyma

Bitoscanat

1,4-Diisothiocyanatobenzol

1,4-Diisothiocyanatobenzol physikalisch-chemischer Eigenschaften

Schmelzpunkt	129-131 °C (lit.)
Siedepunkt	339.4±25.0 °C(Predicted)
Dichte	1.3675 (rough estimate)
Brechungsindex	1.6000 (estimate)
storage temp.	−20°C
Löslichkeit	chloroform: clear
Aggregatzustand	powder
Farbe	white
Wasserlöslichkeit	Hydrolyzes in water.
Sensitive	Moisture Sensitive
Merck	14,1308
BRN	2414340
InChIKey	OMWQUXGVXQELIX-UHFFFAOYSA-N
CAS Datenbank	4044-65-9(CAS DataBase Reference)
EPA chemische Informationen	Bitoscanate (4044-65-9)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	22-36/37/38-42
S-Sätze:	22-26-36/37
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS-Nr.	NX9150000
F	10-21
Hazard Note	Irritant
TSCA	Yes
HazardClass	6.1
PackingGroup	II
HS Code	29291090
Giftige Stoffe Daten	4044-65-9(Hazardous Substances Data)
Toxizität	LD50 oral in mouse: 230mg/kg

Gefahreninformationscode (GHS)

1,4-PHENYLENE DIISOTHIOCYANATE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R42:Sensibilisierung durch Einatmen möglich.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Beschreibung
Bitoscanate is a colorless to beige, odorless,crystalline compound. Molecular weight=192.3; Freezing/Melting point=132℃. Hazard Identification (based onNFPA-704 M Rating System): Health 2, Flammability 1,Reactivity 0.
Chemische Eigenschaften
Those engaged in the manufacture, formulation and application of this anthelmintic compound. Incompatibilities: In general, keep away from strong oxidizers, moisture, strong acids, strong bases. This is a thiocyanate compound. Violent reactions may occur upon contact with chlorates (potassium chlorate, sodium chlorate), nitrates, nitric acid; organic peroxides.
Chemische Eigenschaften
off-white to yellow to beige-grey crystalline
Verwenden
Reagent for solid-phase sequencing.
Verwenden
It is used in the treatment of?hookworms.
Verwenden
anthelmintic
Definition
ChEBI: Bitoscanate is a member of benzenes.
Allgemeine Beschreibung
Odorless colorless crystals. Melting point 132°C.
Reaktivität anzeigen
1,4-PHENYLENE DIISOTHIOCYANATE reacts readily with amines [Noller]. These reactions may generate significant amounts of heat . Emits very toxic fumes of nitrogen oxides and sulfur oxides when heated to decomposition [EPA, 1998].
Health Hazard
1,4-PHENYLENE DIISOTHIOCYANATE is highly toxic if ingested. It is a central nervous system and gastrointestinal toxin in humans.
Brandgefahr
When heated to decomposition, 1,4-PHENYLENE DIISOTHIOCYANATE emits very toxic fumes of nitrogen oxides and sulfur oxides.
Sicherheitsprofil
Poison by ingestion and intraperitoneal routes. Human systemic effects by ingestion: hallucinations, nausea. When heated to decomposition it emits very toxic fumes of NOx,CN,and SOx.See also THIOCYANATES
mögliche Exposition
Those engaged in the manufacture, formulation and application of this anthelmintic compound. Incompatibilities: In general, keep away from strong oxidizers, moisture, strong acids, strong bases. This is a thiocyanate compound. Violent reactions may occur upon contact with chlorates (potassium chlorate, sodium chlorate), nitrates, nitric acid; organic peroxides.
Erste Hilfe
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seekmedical attention immediately. If this chemical contactsthe skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove fromexposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing hasstopped and CPR if heart action has stopped. Transferpromptly to a medical facility. When this chemical hasbeen swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. For cyanide poisoning, use amylnitrate capsules if symptoms develop. All area employeesshould be trained regularly in emergency measures for cyanide poisoning and in CPR. A cyanide antidote kit shouldbe kept in the immediate work area and must be rapidlyavailable. Kit ingredients should be replaced every 1 2years to ensure freshness. Persons trained in the use of thiskit, oxygen use, and CPR must be quickly available.
Lager
Color Code—Green: General storage may be used.Store in tightly closed containers in a cool, well-ventilatedarea. Store under inert gas; moisture sensitive.
Versand/Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1—Poisonous materials, Technical Name Required.
läuterung methode
Purify bitoscanate by recrystallisation from AcOH, pet ether (b 40-60o), Me2CO or aqueous Me2CO. [van der Kerk et al. Recl Trav Chim Pays-Bas 74 1262 1955, Leiber & Slutkin J Org Chem 27 2214 1962, Beilstein 13 IV 174.]
Inkompatibilitäten
Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.

1,4-PHENYLENE DIISOTHIOCYANATE Upstream-Materialien And Downstream Produkte

1,4-Diisothiocyanatobenzol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

4044-65-9, 1,4-PHENYLENE DIISOTHIOCYANATE Verwandte Suche:

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