2-Nitro-m-toluylsure

Bezeichnung:2-Nitro-m-toluylsure

CAS-Nr5437-38-7

Englisch Name:3-Methyl-2-nitrobenzoic acid

CBNumberCB9223457

SummenformelC8H7NO4

Molgewicht181.15

MOL-Datei5437-38-7.mol

Synonyma

2-Nitro-m-toluylsure

2-Nitro-m-toluylsure physikalisch-chemischer Eigenschaften

Schmelzpunkt	220-223 °C (lit.)
Siedepunkt	314.24°C (rough estimate)
Dichte	1.4283 (rough estimate)
Brechungsindex	1.5468 (estimate)
storage temp.	Sealed in dry,Room Temperature
Aggregatzustand	powder to crystal
pka	2.26±0.10(Predicted)
Farbe	White to Almost white
Wasserlöslichkeit	<0.1 g/100 mL at 22 ºC
BRN	1960698
InChI	InChI=1S/C8H7NO4/c1-5-3-2-4-6(8(10)11)7(5)9(12)13/h2-4H,1H3,(H,10,11)
InChIKey	DGDAVTPQCQXLGU-UHFFFAOYSA-N
SMILES	C(O)(=O)C1=CC=CC(C)=C1[N+]([O-])=O
CAS Datenbank	5437-38-7(CAS DataBase Reference)
EPA chemische Informationen	3-Methyl-2-nitrobenzoic acid (5437-38-7)

Sicherheit

Kennzeichnung gefährlicher	Xi,Xn
R-Sätze:	36/37/38-20/21/22
S-Sätze:	26-36-36/37/39-22-37
WGK Germany	3
TSCA	Yes
HS Code	29163990

Gefahreninformationscode (GHS)

3-Methyl-2-nitrobenzoic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S22:Staub nicht einatmen.
Chemische Eigenschaften
white to slightly yellow crystalline powder
Verwenden
2-Nitro-m-toluic Acid, is a building block used for the synthesis of various compounds. It can be used for the synthesis of novel Indolin-2-one derivatives as protein tyrosine phosphatase 1B inhibitors.
Allgemeine Beschreibung
Prisms or white crystalline solid.
Air & Water Reaktionen
Insoluble in water.
Reaktivität anzeigen
3-Methyl-2-nitrobenzoic acid is a nitrated carboxylic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water. Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry.
Brandgefahr
Information concerning the flash point of 3-Methyl-2-nitrobenzoic acid is not available. 3-Methyl-2-nitrobenzoic acid is probably combustible.
läuterung methode
Recrystallise it from EtOH. The methyl ester has m 74o (from MeOH), and the amide [60310-07-8] M 180.1, has m 192o (needles from H2O, prisms from EtOH). [Beilstein 9 H 480, 9 IV 1722.]

3-Methyl-2-nitrobenzoic acid Upstream-Materialien And Downstream Produkte

2-Nitro-m-toluylsure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

5437-38-7, 3-Methyl-2-nitrobenzoic acid Verwandte Suche:

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