2-Methylbenzoesäure

Bezeichnung:2-Methylbenzoesäure

CAS-Nr118-90-1

Englisch Name:o-Toluic acid

CBNumberCB5852905

SummenformelC8H8O2

Molgewicht136.15

MOL-Datei118-90-1.mol

Synonyma

o-Toluylsure

2-Methylbenzoesäure

2-Methylbenzoesäure physikalisch-chemischer Eigenschaften

Schmelzpunkt	102-104 °C (lit.)
Siedepunkt	258-259 °C (lit.)
Dichte	1.062 g/mL at 25 °C (lit.)
Brechungsindex	1.512
Flammpunkt	148 °C
storage temp.	Sealed in dry,Room Temperature
Löslichkeit	1.2g/l
Aggregatzustand	Needle-Like Crystalline Solid
pka	3.91(at 25℃)
Farbe	White to slightly yellow
Wichte	1.062
PH	3.1 (H2O, 20℃)(saturated aqueous solution)
Wasserlöslichkeit	<0.1 g/100 mL at 19 ºC
Merck	14,9535
BRN	1072103
Stabilität	Stable. Combustible. Incompatible with strong oxidizing agents, strong bases.
InChIKey	ZWLPBLYKEWSWPD-UHFFFAOYSA-N
CAS Datenbank	118-90-1(CAS DataBase Reference)
NIST chemische Informationen	Benzoic acid, 2-methyl-(118-90-1)
EPA chemische Informationen	o-Toluic acid (118-90-1)

Sicherheit

Kennzeichnung gefährlicher	Xi,Xn
R-Sätze:	36/37/38-22
S-Sätze:	26-36-22
WGK Germany	3
RTECS-Nr.	XU1400000
TSCA	Yes
HS Code	29163900

Gefahreninformationscode (GHS)

o-Toluic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S22:Staub nicht einatmen.
Chemische Eigenschaften
White crystals. Slightly soluble in water; soluble in alcohol and chloroform. Combustible.
Verwenden
o-Toluic acid is part of a group of Benzoic acid (B203900) derivatives that possess inhibitory activity against mushroom tyrosinases. o-Toluic acid is also used as a reagent to synthesize halogen-substituted benzoic acids (such as 2,4-Dichlorobenzoic acid [D431955]), which have potential muscle stimulating effects.
Verwenden
Bacteriostat.
Definition
ChEBI: A methylbenzoic acid that is benzoic acid substituted by a methyl group at position 2.
Synthesis Reference(s)
Organic Syntheses, Coll. Vol. 2, p. 588, 1943
The Journal of Organic Chemistry, 25, p. 616, 1960 DOI: 10.1021/jo01074a035
Tetrahedron Letters, 22, p. 1013, 1981 DOI: 10.1016/S0040-4039(01)82853-7
Air & Water Reaktionen
Fine dust dispensed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard. . Insoluble in water.
Reaktivität anzeigen
o-Toluic acid is a carboxylic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water. Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry. Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in o-Toluic acid to corrode or dissolve iron, steel, and aluminum parts and containers. Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide. The reaction is slower for dry, solid carboxylic acids. Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat. Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat. A wide variety of products is possible. Like other acids, carboxylic acids may initiate polymerization reactions; like other acids, they often catalyze (increase the rate of) chemical reactions. o-Toluic acid is incompatible with strong oxidizers.
Brandgefahr
Flash point data for o-Toluic acid are not available. o-Toluic acid is probably combustible. Fine dust dispensed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.
läuterung methode
Crystallise the acid from *benzene (2.5mL/g) and dry in air. The S-benzylisothiuronium salt has m 146o (from aqueous EtOH). [Beilstein 9 IV 1697.]

o-Toluic acid Upstream-Materialien And Downstream Produkte

2-Methylbenzoesäure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

118-90-1, o-Toluic acid Verwandte Suche:

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