2,2'-(Nitrosoimino)bisethanol

Bezeichnung:2,2'-(Nitrosoimino)bisethanol

CAS-Nr1116-54-7

Englisch Name:N-NITROSODIETHANOLAMINE

CBNumberCB8401443

SummenformelC4H10N2O3

Molgewicht134.13

MOL-Datei1116-54-7.mol

Synonyma

2,2'-(Nitrosoimino)bisethanol

2,2'-(Nitrosoimino)bisethanol physikalisch-chemischer Eigenschaften

Schmelzpunkt	200 °C (decomp)
Siedepunkt	bp0.01 125°
Dichte	1,26 g/cm³
Brechungsindex	nD20 1.4849
Flammpunkt	11℃
storage temp.	2-8°C
Wasserlöslichkeit	Completely miscible in water
Löslichkeit	DMSO (Soluble), Ethyl Acetate (Sparingly), Methanol (Soluble), Water (Sparingly)
Aggregatzustand	clear liquid to slightly cloudy liquid
pka	13.76±0.10(Predicted)
Farbe	Light yellow to Brown
Merck	14,6634
BRN	1762620
CAS Datenbank	1116-54-7(CAS DataBase Reference)
IARC	2B (Vol. 17, Sup 7, 77) 2000
EPA chemische Informationen	N-Nitrosodiethanolamine (1116-54-7)

Sicherheit

Kennzeichnung gefährlicher	T,F
R-Sätze:	45-11
S-Sätze:	53-45-16
RIDADR	UN 1993 3/PG 2
WGK Germany	1
RTECS-Nr.	KL9550000
HS Code	2922.19.9690
HazardClass	3.1
PackingGroup	II
Giftige Stoffe Daten	1116-54-7(Hazardous Substances Data)
Toxizität	LD50 orl-rat: 7500 mg/kg GISAAA 40(1),81,75

Gefahreninformationscode (GHS)

N-NITROSODIETHANOLAMINE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R45:Kann Krebs erzeugen.
S-Sätze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
Reddish Yellow Oil
Verwenden
A potent liver carcinogen in several species of animals, is one of the most widespread N-nitroso compounds in the human environment.
Definition
ChEBI: N-Nitrosodiethanolamine is a nitroso compound.
Allgemeine Beschreibung
Yellow to dark brown very viscous liquid with no distinct odor.
Air & Water Reaktionen
Water soluble.
Reaktivität anzeigen
N-NITROSODIETHANOLAMINE can react with alkoxides. N-NITROSODIETHANOLAMINE reacts with sulfuric acid at temperatures above 311° F.
Health Hazard
ACUTE/CHRONIC HAZARDS: N-NITROSODIETHANOLAMINE may be harmful by eye or skin contact, inhalation or ingestion. It is an irritant and, when heated to decomposition, it emits toxic fumes of carbon monoxide, carbon dioxide and nitrogen oxides.
Brandgefahr
Flash point data for N-NITROSODIETHANOLAMINE are not available; however, N-NITROSODIETHANOLAMINE is probably combustible.
Sicherheitsprofil
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data.Mildly toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS and ALCOHOLS.
Carcinogenicity
N-Nitrosodiethanolamine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
läuterung methode
Purify NDELA by dissolving the amine (0.5g) in 1-propanol (10mL) and 5g of anhydrous Na2SO4 added with stirring. After standing for 1-2hours, it is filtered and passed through a chromatographic column packed with 10mL of AG 50W x 8 (H+form 50-100mesh, a strongly acidic cation exchanger). The eluent and washings (50 mL EtOH) are combined and evaporated to dryness at 35o. It has also been extracted with EtOH from the nitrosation mixture of ethanolamine, filtered and distilled under high vacuum. [Fukuda et al. Anal Chem 53 2000 1981, Jones & Wilson J Chem Soc 550, 1949, Beilstein 1 III 721, see Spiegelhalder et al. N-Nitroso Compounds: Occurrence Biological Effects and Relevance in Human Cancer (eds. O’Neill et al. IARC Scientific Publications No 57; IARC Lyon p943 1984.] Possible
Filter für giftige stoffe
The Initial Risk Screening Level (IRSL) for n-nitrosodiethanolamine is 0.0012 μg/m3 based on an annual averaging time.

N-NITROSODIETHANOLAMINE Upstream-Materialien And Downstream Produkte

2,2'-(Nitrosoimino)bisethanol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

1116-54-7, N-NITROSODIETHANOLAMINE Verwandte Suche:

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