S-NITROSOGLUTATHIONE Struktur

S-NITROSOGLUTATHIONE

Bezeichnung:S-NITROSOGLUTATHIONE

CAS-Nr57564-91-7

Englisch Name:S-NITROSOGLUTATHIONE

CBNumberCB2664125

SummenformelC10H16N4O7S

Molgewicht336.32

MOL-Datei57564-91-7.mol

S-NITROSOGLUTATHIONE physikalisch-chemischer Eigenschaften

Schmelzpunkt	>170°C (dec.)
Dichte	1.68
Brechungsindex	1.6000 (estimate)
storage temp.	-20°C
Löslichkeit	DMSO (Slightly), Water (Slightly)
Aggregatzustand	Pink solid
pka	2.21±0.10(Predicted)
Farbe	Off-White to Pink
Wasserlöslichkeit	Soluble to 100 mM in water
Stabilität	Hygroscopic
CAS Datenbank	57564-91-7(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36
WGK Germany	3
RTECS-Nr.	MC0558000

Gefahreninformationscode (GHS)

S-NITROSOGLUTATHIONE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
S-Nitroso-L-glutathione is an S-nitrosothiol NO donor based on naturally-occurring glutathione. It is a potent smooth muscle relaxant and inhibitor of platelet aggregation. Its stability in solution varies from seconds to hours depending on temperature, buffer composition, and metal content.
Chemische Eigenschaften
Pink Powder
Verwenden
A carrier of nitric oxide, relaxing smooth muscle and inhibiting platelet activation
Verwenden
S-Nitrosoglutathione (GSNO) has been used:
- as a standard in reversed phase chromatography coupled to chemical vapour generation and atomic fluorescence detector (RPC-CVGAFS) and reversed phase chromatography fluorimetric (RPC-FD).
- as a standard in spectrophotometric and high-performance liquid chromatography (HPLC) assay.
Definition
ChEBI: S-nitrosoglutathione is a glutathione derivative that is glutathione in which the hydrogen attached to the sulfur has been replaced by a nitroso group. It has a role as a platelet aggregation inhibitor, a bronchodilator agent, a nitric oxide donor and a signalling molecule. It is a glutathione derivative and a nitrosothio compound. It is a conjugate acid of a S-nitrosoglutathione(2-).
Allgemeine Beschreibung
A utility carrier of nitric oxide. Breaks down at physiological pH to produce nitric oxide. Causes smooth muscle relaxation and inhibits platelet aggregation. Induces apoptosis in mouse thymocytes. Note: 1 set = 5 x 2.5 mg.
Biologische Aktivität
A carrier of NO, relaxing smooth muscle and inhibiting platelet aggregation.
Biochem/physiol Actions
Product does not compete with ATP.
Lager
Desiccate at -20°C

S-NITROSOGLUTATHIONE Upstream-Materialien And Downstream Produkte

S-NITROSOGLUTATHIONE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

57564-91-7, S-NITROSOGLUTATHIONE Verwandte Suche:

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