SPERMINE NONOATE

SPERMINE NONOATE Chemische Eigenschaften,Einsatz,Produktion Methoden

• S-Sätze Betriebsanweisung:

  S22:Staub nicht einatmen.
  S24/25:Berührung mit den Augen und der Haut vermeiden.

• Beschreibung

  Spermine NONOate (136587-13-8) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner.? ? The half-life of Spermine NONOate in 0.1 M phosphate buffer at pH 7.4 is 39 min at 37 °C, or 230 min at room temperature.1? ? Dissociation is essentially instantaneous at a pH of 5.0.

• Chemische Eigenschaften

  Off-White Solid

• Verwenden

  A reagent which releases Nitric Oxide into aqueous solutions at controlled rates for in vitro studies.

• Allgemeine Beschreibung

  Complex of nitric oxide (NO) with spermine. Convenient reagent for preparing aqueous solutions of NO. Half-life (t_?) of NO release = 230 min (PBS, pH 7.4, 22°C).

• Biologische Aktivität

  A stable complex of nitric oxide and spermine used to generate a controlled release of nitric oxide in solution (EC 50 = 6.2 μ M for relaxation of rabbit aorta, and t=39 min at 37℃, pH 7.4, aqueous solution).

• Biochem/physiol Actions

  Product does not compete with ATP.

• Einzelnachweise

  1) Keefer et al. (1996), “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms; Methods Enzymol., 268 281

SPERMINE NONOATE Upstream-Materialien And Downstream Produkte

SPERMINE NONOATE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(70)Suppliers

136587-13-8, SPERMINE NONOATE Verwandte Suche: