N-Cyclohexyl-N-methylcyclohexanamin

Bezeichnung:N-Cyclohexyl-N-methylcyclohexanamin

CAS-Nr7560-83-0

Englisch Name:N,N-Dicyclohexylmethylamine

CBNumberCB8367888

SummenformelC13H25N

Molgewicht195.34

MOL-Datei7560-83-0.mol

Synonyma

N-Cyclohexyl-N-methylcyclohexylamin

N-Cyclohexyl-N-methylcyclohexanamin

N-Cyclohexyl-N-methylcyclohexanamin physikalisch-chemischer Eigenschaften

Schmelzpunkt	193-194 °C
Siedepunkt	265 °C(lit.)
Dichte	0.912 g/mL at 25 °C(lit.)
Dampfdruck	7.52Pa at 25℃
Brechungsindex	n20/D 1.49(lit.)
Flammpunkt	231 °F
storage temp.	Inert atmosphere,Room Temperature
Löslichkeit	Chloroform (Slightly), Methanol (Slightly)
pka	11.03±0.20(Predicted)
Aggregatzustand	clear liquid
Farbe	Colorless to Light orange to Yellow
Wasserlöslichkeit	740mg/L at 25℃
BRN	2074991
InChI	1S/C13H25N/c1-14(12-8-4-2-5-9-12)13-10-6-3-7-11-13/h12-13H,2-11H2,1H3
InChIKey	GSCCALZHGUWNJW-UHFFFAOYSA-N
SMILES	CN(C1CCCCC1)C2CCCCC2
LogP	3.71 at 25℃
CAS Datenbank	7560-83-0(CAS DataBase Reference)
NIST chemische Informationen	Cyclohexanamine, N-cyclohexyl-N-methyl-(7560-83-0)
EPA chemische Informationen	Cyclohexanamine, N-cyclohexyl-N-methyl- (7560-83-0)

Sicherheit

Kennzeichnung gefährlicher	C
R-Sätze:	22-34
S-Sätze:	26-36/37/39-45
RIDADR	UN 2735 8/PG 2
WGK Germany	2
RTECS-Nr.	HY4190000
F	10-34
TSCA	TSCA listed
HazardClass	8
PackingGroup	III
HS Code	29213000
Speicherklasse	8A - Combustible corrosive hazardous materials
Hazard Classifications	Acute Tox. 4 Oral Skin Corr. 1B
Giftige Stoffe Daten	7560-83-0(Hazardous Substances Data)

Gefahreninformationscode (GHS)

N,N-Dicyclohexylmethylamine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R34:Verursacht Verätzungen.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Verwenden
N,N-Dicyclohexylmethylamine has been employed as:
- catalyst during O-phenylation of tertiary alcohol with organobismuth(V) compounds
- base during Pd-catalyzed 5-endo-trig cyclization of 1-(o-bromophenyl)-2-methylprop-2-en-1-ol
Definition
ChEBI: N-Cyclohexyl-N-methylcyclohexanamine is an amine.
Application
N,N-Dicyclohexylmethylamine has uses similar to those of the other cyclohexylamines, e.g., as a urethane foam catalyst.
synthetische
N,N-Dicyclohexylmethylamine is prepared by methylating dicyclohexylamine with dimethyl sulfate or by the Leuckart – Wallach reaction.
Synthese

88374-60-1

7560-83-0

The general procedure for the synthesis of N-methyldicyclohexylamine from the compound (CAS:88374-60-1) is as follows: phenylboronic acid (1.0 equiv. for aliphatic N-oxides and 1.5 equiv. for pyridine N-oxides) was mixed with tertiary amine N-oxide (1 mmol) in dichloroethane (2 mL) at 80 °C and stirred. Subsequently, the reaction mixture was transferred to a pressure tube and the reaction was continued at 120 °C. The progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was diluted with ethyl acetate and washed sequentially with water and sodium hydroxide solution (1 equiv., 3 x 5 mL). The organic layer was dried with anhydrous sodium sulfate and the solvent was evaporated and purified by column chromatography to afford the target product, N-methyl dicyclohexylamine.
Einzelnachweise
[1] Tetrahedron Letters, 2017, vol. 58, # 10, p. 909 - 913

N,N-Dicyclohexylmethylamine Upstream-Materialien And Downstream Produkte

N-Cyclohexyl-N-methylcyclohexanamin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

7560-83-0, N,N-Dicyclohexylmethylamine Verwandte Suche:

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