N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamidmonohydrochlorid

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H317：Kann allergische Hautreaktionen verursachen.

  H319：Verursacht schwere Augenreizung.

• Sicherheit

  P280：Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Sultopride hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

• Chemische Eigenschaften

  Crystalline Solid

• Originator

  Barnetil,Delagrange,France,1976

• Verwenden

  Dopamine D2-receptor antagonist. An antipsychotic.

• Manufacturing Process

  A solution of 17.22 g of N-ethyl-α-aminomethylpyrrolidine in 360 ml of pyridine is placed in a 1 l balloon flask. A solution of 3.51 g of phosphorus trichloride in 40 ml of pyridine is added at ambient temperature. After the mixture has been stirred for 1 hour, 10 g of 2-methoxy-5-ethylsulfonylbenzoic acid is introduced. The mixture is heated under reflux for 4 ? hours. After cooling, the solvent is evaporated under vacuum and the residue is dissolved in 200 ml of 20% sodium hydroxide. The solution is extracted with 200 ml of chloroform.
  The organic solution is dried and filtered and the solvent is evaporated under vacuum; the residue is dissolved in 150 ml of ethanol and the solution is acidified with hydrochloric acid. The hydrochloride is dried without heating and recrystallized from 100 ml of absolute ethanol. 7.2 g of N-(1-ethyl-2- pyrrolidyl-methyl-2-methoxy-5-ethylsulfonylbenzamide hydrochloride is produced. Melting point: 190°C to 193°C.

• Therapeutic Function

  Neuroleptic

Sultopride hydrochloride Upstream-Materialien And Downstream Produkte

N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamidmonohydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(79)Suppliers

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