Tacrin Produkt Beschreibung

1,2,3,4-TETRAHYDRO-9-ACRIDINAMINE Struktur
321-64-2
  • CAS-Nr.321-64-2
  • Bezeichnung:Tacrin
  • Englisch Name:1,2,3,4-TETRAHYDRO-9-ACRIDINAMINE
  • Synonyma:Tacrin
    C01453;cs12602;CS 12602;AKOS 221-09;Tacrine 321-64-2;BUTTPARK 20\04-06;Tetrahydroaminocrin;TIMTEC-BB SBB003560;Tetrahydroaminacrine;Tetrahydroaminocrine
  • CBNumber:CB7699634
  • Summenformel:C13H14N2
  • Molgewicht:198.26
  • MOL-Datei:321-64-2.mol
Tacrin physikalisch-chemischer Eigenschaften
  • Schmelzpunkt: :183.5℃
  • Siedepunkt: :325.59°C (rough estimate)
  • Dichte :0.9827 (rough estimate)
  • Brechungsindex :1.4400 (estimate)
  • CAS Datenbank :321-64-2(CAS DataBase Reference)

1,2,3,4-TETRAHYDRO-9-ACRIDINAMINE Chemische Eigenschaften,Einsatz,Produktion Methoden

  • Enzyminhibitor This acetylcholinesterase inhibitor (FWfree-base = 198.27 g/mol; CAS 321- 64-2 and 1684-40-8 (HCl)), also known as Tacrine and 1,2,3,4-tetrahydro- 5-aminoacridine, was the first orally available, centrally-acting cholinesterase inhibitor approved for the treatment of Alzheimer's disease. Its use in the U.S. was discontinued out of concerns about its side effects, mainly hepatoxicity and gastrointestinal discomfort. This agent is also a likely DNA intercalator. Target(s): acetylcholinesterase, Ki = 25 nM (1- 3,6,8,12-17); cholinesterase, or butyrylcholinesterase; aldehyde oxidase; ion channels; K+ current; histamine Nmethyltransferase; apyrase, or ATP diphosphohydrolase; aryl-acylamidase.
1,2,3,4-TETRAHYDRO-9-ACRIDINAMINE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Tacrin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
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321-64-2, 1,2,3,4-TETRAHYDRO-9-ACRIDINAMINE Verwandte Suche:
  • 1,2,3,4-Tetrahydro-5-aminoacridine
  • 1,2,3,4-tetrahydro-9-acridinamin
  • 1,2,3,4-tetrahydro-9-amino-acridin
  • 1,2,3,4-Tetrahydro-9-aminoacridine
  • 5-Amino-6,7,8,9-tetrahydroacridine
  • Acridine, 1,2,3,4-tetrahydro-9-amino-
  • Acridine, 9-amino-1,2,3,4-tetrahydro-
  • Acridine, 9-aminotetrahydro-
  • CS 12602
  • cs12602
  • Tetrahydroaminacrine
  • Tetrahydroaminoacridine
  • Tetrahydroaminocrin
  • Tetrahydroaminocrine
  • BUTTPARK 20\04-06
  • 1,2,3,4-TETRAHYDRO-9-ACRIDINAMINE
  • 9-AMINO-1,2,3,4-TETRAHYDROACRIDINE
  • 321-64-2
  • 9-AMINOTETRAHYDROACRIDINE
  • AKOS 221-09
  • TIMTEC-BB SBB003560
  • 1,2,3,4-tetrahydroacridin-9-amine
  • Tacrine (base and/or unspecified salts)
  • 1,2,3,4-Tetrahydro-acridin-9-ylamine
  • C01453
  • Tacrine 321-64-2
  • 1,2,3,4-Tetrahydro-9-acridinamine hydrochloride hydrate, 97%
  • 9-AcridinaMine, 1,2,3,4-tetrahydro-
  • -
  • C13H14N2HClH2O