Cyclohexylisocyanid

Bezeichnung:Cyclohexylisocyanid

CAS-Nr931-53-3

Englisch Name:CYCLOHEXYL ISOCYANIDE

CBNumberCB7469738

SummenformelC7H11N

Molgewicht109.17

MOL-Datei931-53-3.mol

Synonyma

Cyclohexylisocyanid

Cyclohexylisocyanid physikalisch-chemischer Eigenschaften

Schmelzpunkt	6.45°C
Siedepunkt	173-176 °C
Dichte	0.878 g/mL at 25 °C(lit.)
Brechungsindex	n20/D 1.45(lit.)
Flammpunkt	170 °F
storage temp.	Store at +2°C to +8°C.
Aggregatzustand	Liquid
Farbe	Clear colorless to slightly brown
BRN	3662332
Stabilität	Stable. Incompatible with strong acids, strong bases, strong reducing agents, strong oxidizing agents. Flammable.
CAS Datenbank	931-53-3(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xn,T
R-Sätze:	20/21/22-23/24/25
S-Sätze:	36/37-45-24/25
RIDADR	UN 2810 6.1/PG 2
WGK Germany	3
F	10-13-21
HazardClass	6.1
PackingGroup	III
HS Code	29299090

Gefahreninformationscode (GHS)

CYCLOHEXYL ISOCYANIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Chemische Eigenschaften
colourless liquid
Verwenden
Cyclohexyl Isocyanide can be used as novel arginase inhibitors to treat diseases.
Definition
ChEBI: Cyclohexyl isocyanide is an isocyanide having a cyclohexyl group attached to nitrogen. It is a conjugate base of a cyclohexyl isocyanide(1+).
synthetische
CAUTION: Use a well-ventilated hood and take all precautions before using phosgene.
To a flask equipped as in Preparation 3-1 is added 1.27 kg (10.0 moles) of N-cyclohexylformamide, 3.20 liters of triethylamine, and 4.50 liters of methylene chloride. The solution is stirred while phosgene is rapidly added (300-400 gm/hr) to cause vigorous refluxing. Refluxing ceases after 1.04 kg (10.2 moles) of phosgene have been added and the addition is stopped. The reaction mixture is cooled to 22-25°C, 400 gm (23.5 moles) of ammonia gas added over a period of 1-2 hr, the mixture filtered then concentrated under reduced pressure, and the residue distilled to afford 955 gm (88%), b.p. 67-72°C (14 mm Hg).
Allgemeine Beschreibung
Cyclohexyl isocyanide reacts with dimethyl acetylenedicarboxylate to give a mixture of cyclopenta[b]pyridine derivatives, azaspirononatriene derivative and the azabicyclononatriene. It reacts with dialkyl acetylenedicarboxylates to form 1:1 intermediate which on facile addition to 1-benzylisatin and tryptantrin yields highly functionalized novel unsaturated γ-spiroiminolactones.

CYCLOHEXYL ISOCYANIDE Upstream-Materialien And Downstream Produkte

Cyclohexylisocyanid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

931-53-3, CYCLOHEXYL ISOCYANIDE Verwandte Suche:

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