Ethylfumarat

Bezeichnung:Ethylfumarat

CAS-Nr2459-05-4

Englisch Name:Monoethyl fumarate

CBNumberCB7231119

SummenformelC6H8O4

Molgewicht144.13

MOL-Datei2459-05-4.mol

Synonyma

Ethylfumarat

Ethylfumarat physikalisch-chemischer Eigenschaften

Schmelzpunkt	66-68 °C (lit.)
Siedepunkt	147 °C/16 mmHg (lit.)
Dichte	1.1109
Brechungsindex	1.4500 (estimate)
storage temp.	Refrigerator
Löslichkeit	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Aggregatzustand	Crystalline Powder
pka	3.45±0.10(Predicted)
Farbe	Almost white to beige
Wasserlöslichkeit	Soluble in water.
BRN	1723588
Dielectric constant	6.5（23.0℃）
CAS Datenbank	2459-05-4(CAS DataBase Reference)
NIST chemische Informationen	Ethyl hydrogen fumarate(2459-05-4)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36
WGK Germany	1
HazardClass	IRRITANT
HS Code	29171900

Gefahreninformationscode (GHS)

Monoethyl fumarate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
ALMOST WHITE TO BEIGE CRYSTALLINE POWDER
Verwenden
Monoethyl fumarate is the monoethyl ester form of fumaric acid. Monoethyl fumarate is a kind of effective preservative and polymerization agent for macromolecular material.
Monoethyl fumarate (fumaric acid monoethyl ester, monoethyl fumarate) was used in the preparation of photo-crosslinkable macromers. It was also used to synthesize Ugi/intramolecular Diels-Alder (IMDA) cycloaddition products.
Definition
ChEBI: Monomethyl fumarate is a dicarboxylic acid monoester resulting from the formal condensation of one of the carboxy groups of fumaric acid with methanol. Is is a metabolite of dimethyl fumarate and used for the the treatment of patients with relapsing multiple sclerosis (MS). It also induces the NFE2L2 (Nrf2) transcription factor by binding to KEAP1. It has a role as an immunomodulator, an antioxidant and a drug metabolite. It is an enoate ester, a methyl ester and a dicarboxylic acid monoester. It derives from a fumaric acid.
synthetische
Monomethyl fumarate was synthesized by maleic anhydride and methanol. It is used to treat relapsing forms of multiple sclerosis in adults (including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease).

Monoethyl fumarate Upstream-Materialien And Downstream Produkte

Ethylfumarat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

2459-05-4, Monoethyl fumarate Verwandte Suche:

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