Dinatrium-5,5'-azodisalicylat

Bezeichnung:Dinatrium-5,5'-azodisalicylat

CAS-Nr6054-98-4

Englisch Name:Olsalazine sodium

CBNumberCB7197367

SummenformelC14H11N2NaO6

Molgewicht326.24

MOL-Datei6054-98-4.mol

Synonyma

Dinatrium-5,5'-azodisalicylat

Dinatrium-5,5'-azodisalicylat physikalisch-chemischer Eigenschaften

Schmelzpunkt	240 °C
storage temp.	Inert atmosphere,Store in freezer, under -20°C
Löslichkeit	Sparingly soluble in water, soluble in dimethyl sulfoxide, very slightly soluble in methanol.
Aggregatzustand	Solid
Farbe	Light Yellow to Yellow
CAS Datenbank	6054-98-4(CAS DataBase Reference)
EPA chemische Informationen	Benzoic acid, 3,3'-azobis[6-hydroxy-, disodium salt (6054-98-4)

Sicherheit

HS Code

2927.00.5000

Gefahreninformationscode (GHS)

Olsalazine sodium Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften
Yellow Crystalline Powder
Verwenden
Mordant dye for wool.
Verwenden
Dimer of Mesalazine (M258100), an anti-inflammatory drug used in the treatment of inflammatory bowel disease and ulcerative colitis.
Verwenden
Dimer of Mesalamine. It is an anti-inflammatorydrug used in the treatment of inflammatory bowel disease and ulcerative colitis
synthetische
5-Amino-2-chlorobenzoic acid diazotization, coupled with 2-Hydroxybenzoic acid, and then in a certain pressure and contains trace copper powder or Cupric oxide of Sodium hydroxide solution common heating (130 ~ 150 ℃).
Definition
ChEBI: An organic sodium salt that is the disodium salt of 3,3'-azobis(6-hydroxybenzoic acid) (olsalazine). Effective in the treatment of inflammatory bowel disease and ulcerative colitis. Mechanism of action unknown, but appears to be topical
Trademarks
Dipentum (UCB).
Clinical Use
Induction and maintenance of remission in ulcerative colitis
Stoffwechsel
Olsalazine is broken down by the colonic bacterial flora into 2 molecules of 5-aminosalicylic acid (mesalazine).
The small amounts (1-2% of the dose or less) of intact olsalazine that are absorbed are excreted mainly in urine.
Approximately 0.1% of an oral dose of olsalazine is hepatically metabolised to olsalazine-O-sulfate (olsalazine-S), which has a half-life of 7 days.

Properties and Applications

deep green light yellow. Soluble in water for green light yellow, moderate soluble in Etanol for green yellow. In concentrated sulfuric acid for yellow orange, dilution after light yellow, In concentrated nitric acid to red. Dye aqueous solution to join concentrated hydrochloric acid color greatly shallow for yellow; Join concentrated Sodium hydroxide solution for golden orange.

Standard	Ironing Fastness	Light Fastness	Fulling		Persperation Fastness	Soaping	Water
Standard	Ironing Fastness	Light Fastness	Alkali	Acid	Persperation Fastness	Soaping	Water
ISO	4-5	6	4-5	2-3	4-5	5	5
AATCC	5	6-7	4		5	5	5

Olsalazine sodium Upstream-Materialien And Downstream Produkte

Dinatrium-5,5'-azodisalicylat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

6054-98-4, Olsalazine sodium Verwandte Suche:

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