N-Methyl-N-(1-methylethyl)-N-(2-((9H-xanthen-9-yl-carbonyl)oxy)ethyl)-2-propanaminium-bromid

Bezeichnung:N-Methyl-N-(1-methylethyl)-N-(2-((9H-xanthen-9-yl-carbonyl)oxy)ethyl)-2-propanaminium-bromid

CAS-Nr50-34-0

Englisch Name:Propantheline bromide

CBNumberCB6444482

SummenformelC23H30BrNO3

Molgewicht448.39

MOL-Datei50-34-0.mol

Synonyma

Propanthelinbromid

N-Methyl-N-(1-methylethyl)-N-(2-((9H-xanthen-9-yl-carbonyl)oxy)ethyl)-2-propanaminium-bromid

N-Methyl-N-(1-methylethyl)-N-(2-((9H-xanthen-9-yl-carbonyl)oxy)ethyl)-2-propanaminium-bromid physikalisch-chemischer Eigenschaften

Schmelzpunkt	159-161°C
Dichte	1.2916 (rough estimate)
Brechungsindex	1.6200 (estimate)
storage temp.	2-8°C
Löslichkeit	H2O: soluble50mg/mL
Aggregatzustand	powder
Farbe	white to off-white
Wasserlöslichkeit	>=10 g/100 mL at 21 ºC
Stabilität	Stable. Combustible. Incompatible with strong oxidizing agents.
EPA chemische Informationen	Propantheline bromide (50-34-0)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	22
S-Sätze:	36
WGK Germany	3
RTECS-Nr.	BP8249200
HS Code	2932992000

Gefahreninformationscode (GHS)

Propantheline bromide Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
white crystalline powder
Verwenden
A muscarinic acetylcholine receptor antagonist
Verwenden
anticholinergic
Verwenden
Propantheline is an antimuscarinic agent used in the treatment of hyperhidrosis (excessive sweating), enuresis (involuntary urination) as well as cramps or spasms of the stomach, intestine and bladder.
Definition
ChEBI: Propantheline bromide is a member of xanthenes.
Trademarks
Pro-Banthine (Searle).
Allgemeine Beschreibung
Propantheline bromide,2-hydroxy-ethyl)diisopropylmethylammonium bromidexanthene-9-carboxylate (Pro-Banthine), is prepared in amanner exactly analogous to that used for methanthelinebromide. It is a white, water-soluble, crystalline substance,with properties quite similar to those of methantheline bromide.Its chief difference from methantheline bromide is inits potency, which has been estimated variously to be 2 to5 times as great.
Allgemeine Beschreibung
White crystals or white powder. Melting point 159-161°C .Used therapeutically as an anticholinergic.
Air & Water Reaktionen
Water soluble.
Health Hazard
SYMPTOMS: Symptoms of exposure to Propantheline bromide include dilated pupils and blurred vision; increased intraocular tension and heart rate; hot, dry, red skin; dry mouth; disorientation; hallucinations; aggressive behavior; rapid pulse and respiration; convulsions; and coma.
Brandgefahr
Flash point data are not available for Propantheline bromide , but Propantheline bromide is probably combustible.
Biochem/physiol Actions
Inhibits action of acetylcholine at post-ganglionic synapses; muscarinic acetylcholine receptor antagonist; antispasmodic; reduces gastric acid secretion.
Veterinary Drugs and Treatments
In small animal medicine propantheline bromide has been used for its antispasmodic/antisecretory effects in the treatment of diarrhea. It is also employed in the treatment of hyperreflexic detrusor or urge incontinence and as oral treatment in anticholinergic responsive bradycardias. In horses, propantheline has been used intravenously to reduce colonic peristalsis and for relaxing the rectum to allow easier rectal examination and surgery.

Propantheline bromide Upstream-Materialien And Downstream Produkte

N-Methyl-N-(1-methylethyl)-N-(2-((9H-xanthen-9-yl-carbonyl)oxy)ethyl)-2-propanaminium-bromid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

50-34-0, Propantheline bromide Verwandte Suche:

Send Inquriy