Chinidingluconat

Bezeichnung:Chinidingluconat

CAS-Nr7054-25-3

Englisch Name:QUINIDINE GLUCONATE

CBNumberCB6404879

SummenformelC26H36N2O9

Molgewicht520.57

MOL-Datei7054-25-3.mol

Synonyma

Chinidingluconat

Chinidingluconat physikalisch-chemischer Eigenschaften

Schmelzpunkt

175-176 C

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	20/21/22-36/37/38
S-Sätze:	36-26
RIDADR	1544
WGK Germany	3
RTECS-Nr.	LZ5250000
HazardClass	6.1(b)
PackingGroup	III
HS Code	2939200050

Gefahreninformationscode (GHS)

QUINIDINE GLUCONATE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Verwenden
Quinidine Gluconate is a salt of Quinidine (Q685000), a dextrorotatory stereoisomer of Quinine. Antiarrhythmic (class IA). Antimalarial.
Verwenden
Cardiac depressant (anti-arrhythmic).
Definition
ChEBI: Quinidine D-gluconate is a D-gluconate adduct. It is functionally related to a quinidine.
Trademarks
Duraquin (Warner Chilcott); Quinaglute (Berlex).
Allgemeine Beschreibung
Quinidinium gluconate(Duraquin, Quinaglute) occurs as an odorless, very bitter,white powder. In contrast with the sulfate salt, it is freelysoluble in water. This is important because there are emergencieswhen the condition of the patient and the need for arapid response make the oral route of administration inappropriate.The high water solubility of the gluconate saltalong with a low irritant potential makes it valuable when aninjectable form is needed in these emergencies. Quinidinegluconate forms a stable aqueous solution. When used for injection, it usually contains 80 mg/mL, equivalent to 50 mgof quinidine or 60 mg of quinidine sulfate.
Veterinary Drugs and Treatments
Quinidine is used in small animal or equine medicine for the treatment of ventricular arrhythmias (VPCs, ventricular tachycardia), refractory supraventricular tachycardias, and supraventricular arrhythmias associated with anomalous conduction in Wolff- Parkinson-White (WPW) syndrome. Chronic use of quinidine for controlling ventricular arrhythmias and supraventricular tachycardia in dogs has diminished over the years as other drugs appear to be more effective. It is still used in dogs and horses to convert atrial fibrillation to sinus rhythm. Oral therapy is generally not used in cats.

Chinidingluconat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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