Mepivacainhydrochlorid

Bezeichnung:Mepivacainhydrochlorid

CAS-Nr1722-62-9

Englisch Name:Mepivacaine hydrochloride

CBNumberCB6302306

SummenformelC15H22N2O.ClH

Molgewicht282.81

MOL-Datei1722-62-9.mol

Synonyma

Mepivacainhydrochlorid

Mepivacainhydrochlorid physikalisch-chemischer Eigenschaften

Schmelzpunkt	255-257°C (dec.)
storage temp.	2-8°C
Löslichkeit	H2O: soluble20mg/mL, clear
Aggregatzustand	powder
Farbe	white to beige
InChI	InChI=1S/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H
InChIKey	RETIMRUQNCDCQB-UHFFFAOYSA-N
SMILES	C1(=C(C)C=CC=C1C)NC(=O)C1CCCCN1C.Cl
CAS Datenbank	1722-62-9(CAS DataBase Reference)
EPA chemische Informationen	2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride (1722-62-9)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	22
S-Sätze:	22-24/25
RIDADR	UN 2811 6.1 / PGIII
RTECS-Nr.	TK6475000
HS Code	29333990
Toxizität	LD50 in mice, rats (mg/kg): 280, 500 s.c. (Aberg)

Gefahreninformationscode (GHS)

Mepivacaine hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
White Solid
Verwenden
Mepivacaine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.
Verwenden
An anti-inflammatory and analgesic
Verwenden
anesthetic (local)
Definition
ChEBI: The hydrochloride salt of mepivacaine. It is used as a local anaesthetic.
Trademarks
Arestocaine Hydrochloride (Solvay Pharmaceuticals); Carbocaine (Hospira); Isocaine Hydrochloride(Novocol); Polocaine (AstraZeneca); Polocaine (Dentsply); Scandonest (Deproco).
Biologische Funktion
Mepivacaine hydrochloride (Carbocaine) is longer acting than lidocaine and has a more rapid onset of action (3–5 minutes). Topical application is not effective. It has been widely used in obstetrics, but its use has declined recently because of the early transient neurobehavioral effects it produces. Adverse reactions associated with mepivacaine are generally similar to those produced by other local anesthetics. It can be used with epinephrine or levonordefrin (dental use only).
Allgemeine Beschreibung
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Mepivacaine hydrochloride is a local anesthetic that is related chemically and pharmacologically to the amide-type local anesthetics. It is often administered via local infiltration, peripheral nerve block, etc.
Biochem/physiol Actions
Local anesthetic. Reversibly blocks transient Na+ inward current, as well as the steady-state K+ outward current. Blocks tandem pore (TASK) and Kv1.5, potassium channels in model systems.
Sicherheitsprofil
skin irritant. Questionable carcinogen with

Mepivacaine hydrochloride Upstream-Materialien And Downstream Produkte

Mepivacainhydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

1722-62-9, Mepivacaine hydrochloride Verwandte Suche:

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