Phenanthridine Struktur

Phenanthridin

Bezeichnung:Phenanthridin

CAS-Nr229-87-8

Englisch Name:Phenanthridine

CBNumberCB6239037

SummenformelC13H9N

Molgewicht179.22

MOL-Datei229-87-8.mol

Synonyma

Phenanthridin

Phenanthridin physikalisch-chemischer Eigenschaften

Schmelzpunkt	104-107 °C (lit.)
Siedepunkt	349 °C/769 mmHg (lit.)
Dichte	1.1255 (rough estimate)
Brechungsindex	1.7270 (estimate)
Flammpunkt	100 °C
Löslichkeit	phosphate buffer: soluble
pka	5.58(at 20℃)
Aggregatzustand	Powder
Farbe	White to beige
Wasserlöslichkeit	0.3g/L(20 ºC)
BRN	120204
CAS Datenbank	229-87-8(CAS DataBase Reference)
EPA chemische Informationen	Phenanthridine (229-87-8)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	22-37/38-41
S-Sätze:	26-39
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS-Nr.	SF7928000
HS Code	29333990
Toxizität	mic-bac-sat 50 mg/plate 50NNAZ7,73,83

Gefahreninformationscode (GHS)

Phenanthridine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R37/38:Reizt die Atmungsorgane und die Haut.
R41:Gefahr ernster Augenschäden.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S39:Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
white to beige powder
History
Phenanthridine was first discovered by Ame Pictet and H. J. Ankersmit in 1891 by pyrolysis of the condensed product of benzaldehyde and aniline. Earlier, phenanathridine and related compounds were prepared using mainly Pictect-Hurbert and modified Morgan-Walls type of condensation reactions.
Verwenden
Phenanthridine is an isomeric compound of acridine. It is a nitrogen heterocycle that is the basis of DNA-binding fluorescent dyes through intercalation. Ethidium bromide and propidium iodide are the examples of such intercalating dyes. It is used as a dye in biological and chemical sensors. It is also used in the study of ecotoxicity and rotational spectroscopic investigations and radio astronomical searches.
synthetische
Palladium catalyzed synthesis of phenanthridine has been accomplished by Pritchard and coworkers from imidoyl selenides. This was the first report of palladium insertion into the C-Se bond. The palladium insertion into the imidoyl selenides 3.20 followed by intramolecular cyclization and subsequent aromatization via the elimination of HSePh lead to the formation of substituted phenanthridines 3.21.

Pd-catalysed synthesis of phenanathridine
Definition
ChEBI: Phenanthridine is an azaarene that is the 9-aza derivative of phenanthrene. The parent of the class of phenanthridines. It is a mancude organic heterotricyclic parent, a polycyclic heteroarene, a member of phenanthridines and an azaarene.
Synthesis Reference(s)
Journal of the American Chemical Society, 74, p. 6295, 1952 DOI: 10.1021/ja01144a521
Journal of Heterocyclic Chemistry, 26, p. 865, 1989 DOI: 10.1002/jhet.5570260366
Tetrahedron Letters, 29, p. 5463, 1988 DOI: 10.1016/S0040-4039(00)80787-X
Allgemeine Beschreibung
Phenanthridine appears as crystalline needles. Mutagenic.
Air & Water Reaktionen
Sparingly soluble in water.
Reaktivität anzeigen
PHENANTHRIDINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Brandgefahr
Flash point data are not available for PHENANTHRIDINE, but is probably combustible.
Sicherheitsprofil
Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.

Phenanthridine Upstream-Materialien And Downstream Produkte

Phenanthridin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

229-87-8, Phenanthridine Verwandte Suche:

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