Omethoat (ISO)

Bezeichnung:Omethoat (ISO)

CAS-Nr1113-02-6

Englisch Name:Omethoate

CBNumberCB6109938

SummenformelC5H12NO4PS

Molgewicht213.19

MOL-Datei1113-02-6.mol

Synonyma

Omethoat

Omethoat (ISO)

Omethoat (ISO) physikalisch-chemischer Eigenschaften

Schmelzpunkt	-27.9°C
Siedepunkt	135°C
Dichte	1.3200
Dampfdruck	3.3×10^-3Pa (20 °C)
Flammpunkt	100 °C
storage temp.	0-6°C
Löslichkeit	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Wasserlöslichkeit	Miscible
pka	14.40±0.46(Predicted)
Aggregatzustand	liquid
BRN	1785256
Stabilität	Hygroscopic
CAS Datenbank	1113-02-6(CAS DataBase Reference)
NIST chemische Informationen	Omethoate(1113-02-6)
EPA chemische Informationen	Omethoate (1113-02-6)

Sicherheit

Kennzeichnung gefährlicher	T+;N,N,T+,T
R-Sätze:	21-25-50
S-Sätze:	1/2-23-36/37-45-61
RIDADR	3018
WGK Germany	3
RTECS-Nr.	TF8050000
HazardClass	6.1(a)
PackingGroup	II
HS Code	29309090
Giftige Stoffe Daten	1113-02-6(Hazardous Substances Data)
Toxizität	LD50 oral in rabbit: 50mg/kg

Gefahreninformationscode (GHS)

Omethoate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R21:Gesundheitsschädlich bei Berührung mit der Haut.
R25:Giftig beim Verschlucken.
R50:Sehr giftig für Wasserorganismen.
S-Sätze Betriebsanweisung:
S1/2:Unter Verschluss und für Kinder unzugänglich aufbewahren.
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Verwenden
Omethoate is a systemic insecticide used for the control of (mostly) sucking insects and mites in a wide variety of crops.
Verwenden
Insecticidal, acaricidal, and fungicidal combinations of carboxamides and other pesticides.
Definition
ChEBI: Omethoate is an organic thiophosphate and an organothiophosphate insecticide. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an acaricide and an agrochemical. It is functionally related to a N-methyl-2-sulfanylacetamide.
Kontakt-Allergie
Contact dermatitis from omethoate-dimethoxon is rare.
Stoffwechselwegen
Omethoate is the P=O analogue (oxon) of dimethoate. Dimethoate is metabolised via oxidative desulfuration to omethoate which is the active anti-acetylcholinesterase metabolite. This biotransformation occurs in all media: hence the metabolic pathways of both compounds have much in common. However, degradative pathways acting directly on dimethoate such as O-demethylation, N-demethylation and hydrolysis of the amide function mean that the balance between activation and degradative metabolism will influence their respective selective toxicities. In mammals there are two main routes of degradation: (i) glutathione transferase mediated O-demethylation (ii) hydrolysis to N-methylthioglycolamide which is S-methylated by S-adenosylmethionine and subsequently thiooxidised. In soil and plants the N-methylthioglycolamide moiety formed from the hydrolysis of omethoate undergoes a complex series of C₁, C₂ and C₃ biotransformations ultimately leading to oxalate and citrate respectively and total degradation to C0₂. The information reported below is derived largely from an evaluation prepared by the UK MAFF Pesticide Safety Directorate (PSD, 1993).
Stoffwechsel
Orally administered omethoate to rats is rapidly metabolized and excreted in the urine; the main metabolites are O-demethylomethoate and N-methyl-2- methylsulfinylacetamide. O-Demethylation and hydrolysis of the P?S bond are main degradation routes both in mammals and plants. Omethoate is rapidly degraded in soils with DT₅₀ of a few days.
Degradation
Omethoate was slowly hydrolysed in acidic media but more rapidly under alkaline conditions. The half-lives for hydrolysis at pH 4,7, and 9 were 102 days, 17 days and 28 hours, respectively (PM). Omethoate does not absorb light at wavelengths above 250 nm and it is thus unlikely to be subject to photodecomposition. An aqueous solution of omethoate was irradiated for 14 hours with a high pressure filtered mercury vapour lamp without detectable photolysis occurring (PSD, 1993).
Toxicity evaluation
The acute oral LD₅₀ for rats is about 25 mg/kg. Inhalation LC50 (4 h) for rats is 0.3 mg/L air. ADI is 0.3 μg/kg b.w.

Omethoate Upstream-Materialien And Downstream Produkte

1113-02-6, Omethoate Verwandte Suche:

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