Fenhexamid

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Achtung

• Gefahrenhinweise

  H411：Giftig für Wasserorganismen, mit langfristiger Wirkung.

• Sicherheit

  P273：Freisetzung in die Umwelt vermeiden.

  P391：Verschüttete Mengen aufnehmen.

  P501：Inhalt/Behälter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Fenhexamid Chemische Eigenschaften,Einsatz,Produktion Methoden

• R-Sätze Betriebsanweisung:

  R51/53:Giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.

• S-Sätze Betriebsanweisung:

  S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.

• Beschreibung

  Fenhexamid is a foliar fungicide. It has a moderate aqueous solubility, a low risk of leaching to groundwater and is relatively volatile. It is not persistent in soil or aquatic systems. It has a low mammalian toxicity and these is a slight concern regarding its potential to bioaccumulate. No serious human health risks have been identified. It is moderately toxic to birds, most aquatic organisms and earthworms. The risk to honeybees is low.

• Verwenden

  Hydroxyanilide fungicide.

• Definition

  ChEBI: Fenhexamid is an aromatic amide resulting from the formal condensation of the carboxy group of 1-methylcyclohexanecarboxylic acid with the amino group of 4-amino-2,3-dichlorophenol. It has a role as an EC 1.14.13.72 (methylsterol monooxygenase) inhibitor, a sterol biosynthesis inhibitor and an antifungal agrochemical. It is a dichlorobenzene, a monocarboxylic acid amide, a member of phenols, an aromatic amide and an anilide fungicide.

• Vorbereitung Methode

  Fenhexamid is commercially produced through a multi-step chemical synthesis that begins with the reaction of 2,3-dichloro-4-hydroxyaniline and 1-methylcyclohexanoyl chloride in ethyl acetate. The mixture is heated to around 78 DegC for a reflux reaction, during which triethylamine is added dropwise to neutralize the hydrochloric acid formed. This step facilitates the formation of the key amide bond in fenhexamid’s structure. After maintaining reflux for approximately two hours, the reaction mixture is cooled and filtered to isolate the product.

• Hazard

  Low toxicity by ingestion, inhalation, and skin contact.

• Landwirtschaftliche Anwendung

  Fungicide: Fungicide; for control of Botrytis cinerea and related diseases on Rubus, Ribes, bushberries, caneberries, grapes, pistachios, strawberries, ornamentals and other crops. Control of Monilinia diseases of almonds and stone fruit. On grapes and grapevines for suppression of powdery mildew and to control bunch rot[83].

• Handelsname

  KBR-2738

• Toxicity evaluation

  Low toxicity, high safety: Acute oral LD₅₀ (rats): males > 5000 mg/kg; acute dermal LD₅₀ (rats, 24 hours): > 5000 mg/kg; acute inhalation LC₅₀ (4 hours, rats): > 5057 mg/kg air. Non-irritating to rabbit skin and eyes; no teratogenic or carcinogenic effects.

• Mode of action

  Fenhexamid is a systemic, protective amide fungicide developed by Bayer in 1989. Its mode of action involves inhibiting sterol biosynthesis—specifically by targeting 3-ketoreductase—to prevent C4 demethylation, which halts fungal conidiophore and hyphal growth. This unique mechanism provides excellent activity against resistant strains. Furthermore, it can be formulated with various active ingredients, such as tebuconazole, fenarimol, carbendazim, flupyrazole, pyraclostrobin, and imazalil.

• Einzelnachweise

  [1] Xu, Xinxin et al. “A strategy for the free-formulation application of hydrophobic pesticides: achieving efficient and multifunctional utilization to promote green and sustainable agriculture.” Pest Management Science 81 7 (2025): 4016–4026.https://doi.org/10.1002/ps.8776

• Pestizidtyp

  Fungicide

Fenhexamid Upstream-Materialien And Downstream Produkte

Fenhexamid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(188)Suppliers

126833-17-8, Fenhexamid Verwandte Suche: