Sucroseoctaacetat

Bezeichnung:Sucroseoctaacetat

CAS-Nr126-14-7

Englisch Name:Sucrose octaacetate

CBNumberCB4296191

SummenformelC28H38O19

Molgewicht678.59

MOL-Datei126-14-7.mol

Synonyma

Sucroseoctaacetat

Sucroseoctaacetat physikalisch-chemischer Eigenschaften

Schmelzpunkt	82-85 °C(lit.)
alpha	D25.4 +58.5° (c = 2.56 in abs alcohol)
Siedepunkt	260 °C(lit.)
Dichte	1.28
FEMA	3038 \| SUCROSE OCTAACETATE
Brechungsindex	60 ° (C=2, EtOH)
storage temp.	Inert atmosphere,Room Temperature
Löslichkeit	Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
Aggregatzustand	Powder
Farbe	White to creamy white
Geruch (Odor)	odorless
Geruchsart	odorless
Optische Aktivität	[α]22/D +58.8°, c = 2.5 in ethanol
Wasserlöslichkeit	SLIGHTLY SOLUBLE
Merck	14,8881
BRN	79290
InChIKey	ZIJKGAXBCRWEOL-SAXBRCJISA-N
LogP	3.19
CAS Datenbank	126-14-7(CAS DataBase Reference)
NIST chemische Informationen	Sucrose, octaacetate(126-14-7)
EPA chemische Informationen	Sucrose octaacetate (126-14-7)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	24/25-37/39-26
WGK Germany	2
RTECS-Nr.	WN6620000
F	3
HS Code	29400090
Toxizität	LD50 orally in Rabbit: 5000 mg/kg LD50 dermal Rabbit 5000 mg/kg

Sucrose octaacetate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
white to creamy white powder
Chemische Eigenschaften
Sucrose octaacetate is odorless with an intensly bitter flavor influenced by food acids
Chemische Eigenschaften
Sucrose octaacetate occurs as white hygroscopic powder. It is practically odorless with a bitter taste.
Verwenden
LC-MS Analysis of Sucralose and Sucrose Octacetate on Ascentis RP-Amide
Verwenden
Adhesive; impregnating and insulating papers; in lacquers and plastics; as a denaturant for alcohol.
Verwenden
Octa-O-acetyl D-(+)-Surcose was used in studies involving human bitter taste receptor hTAS2R46.
Definition
ChEBI: Sucrose octaacetate is a glycoside.
Vorbereitung Methode
Sucrose octaacetate is typically produced by chemical synthesis; one reported synthetic method is by pyridine-catalyzed acetylation of sucrose.
synthetische
May be prepared by heating sucrose, acetamide and sodium acetate; or by acetylation of sucrose using acetic anhydride, zinc chloride and acetic acid.
Pharmazeutische Anwendungen
Sucrose octaacetate is used as an alcohol denaturant in pharmaceutical formulations. It is also used as a bittering agent, and is incorporated into preparations intended to deter nail-biting or thumb-sucking.
Sicherheitsprofil
Slightly toxic by ingestion andskin contact. A skin irritant. When heated todecomposition it emits acrid smoke and irritating vapors.
Sicherheit(Safety)
Sucrose octaacetate is generally regarded as safe. It is considered slightly hazardous in cases of skin contact (irritant), ingestion, or inhalation.
LD50 (rabbit, skin): >5 g/kg
LD50 (rat, oral): >5 g/kg
Lager
Sucrose octaacetate is a stable material and should be stored in a well-closed, airtight container. Store in a cool, dry place; moisture may cause instability.
läuterung methode
After three recrystallisations from EtOH or 95% EtOH (charcoal), the m of the octaacetate rises to 88-90o, or Et2O with m 89o and [] D +58.5o (c 2.6, EtOH). It has a bitter taste. [Linstead et al. J Am Chem Soc 62 3260 1940, Lemieux & Huber J Am Chem Soc 78 4117 1956, Beilstein 17/8 V 410.]
Regulatory Status
GRAS listed. Approved by the FDA as both a direct and an indirect food additive, and as a nail-biting deterrent for over-the-counter drug products.

Sucrose octaacetate Upstream-Materialien And Downstream Produkte

Sucroseoctaacetat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

126-14-7, Sucrose octaacetate Verwandte Suche:

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