Pyridin-2-thiol-1-oxid,Natriumsalz

Bezeichnung:Pyridin-2-thiol-1-oxid,Natriumsalz

CAS-Nr3811-73-2

Englisch Name:Sodium Pyrithione

CBNumberCB3352724

SummenformelC5H6NNaOS

Molgewicht151.16

MOL-Datei3811-73-2.mol

Synonyma

Pyridin-2-thiol-1-oxid, Natriumsalz

Pyridin-2-thiol-1-oxid,Natriumsalz

Pyridin-2-thiol-1-oxid,Natriumsalz physikalisch-chemischer Eigenschaften

Schmelzpunkt	-25 °C
Siedepunkt	109 °C
Dichte	1.22
Dampfdruck	0-0Pa at 25℃
Brechungsindex	1.4825
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
Löslichkeit	H₂O: 0.1 M at 20 °C, clear, faintly yellow
Aggregatzustand	Solution
Farbe	very deep brown
Biologische Quelle	synthetic
Wasserlöslichkeit	54.7 g/100 mL
maximale Wellenlänge (λmax)	334nm(H2O)(lit.)
Sensitive	Hygroscopic
Merck	14,7994
BRN	4026050
InChI	1S/C5H5NOS.Na/c7-6-4-2-1-3-5(6)8;/h1-4,8H;/q;+1/p-1
InChIKey	WNGMMIYXPIAYOB-UHFFFAOYSA-M
SMILES	O.[O-][n+]1ccccc1S[Na]
LogP	-2.38 at 20℃ and pH7
Oberflächenspannung	65.013-72.6mN/m at 1-1.02g/L and 20-20.1℃
CAS Datenbank	3811-73-2(CAS DataBase Reference)
EPA chemische Informationen	Sodium (2-pyridylthio)-N-oxide (3811-73-2)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	22-36/37/38-36/38
S-Sätze:	26-36-24/25-37/39
RIDADR	UN 3334
WGK Germany	3
RTECS-Nr.	UT9000000
F	3-13
TSCA	TSCA listed
HS Code	29333990
Speicherklasse	6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
Hazard Classifications	Acute Tox. 3 Dermal Acute Tox. 3 Inhalation Acute Tox. 4 Oral Aquatic Acute 1 Aquatic Chronic 2 Eye Irrit. 2 Skin Irrit. 2 Skin Sens. 1 STOT RE 1

Gefahreninformationscode (GHS)

Sodium Pyrithione Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R36/38:Reizt die Augen und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Beschreibung
Sodium pyrithione is mainly used for anti-mildew and antibacterial products in the fields of daily chemicals (shampoo and hair care products), architectural coatings, adhesives, sealants, pesticides, textiles, leather products, metal working fluids, etc. It can also be formulated for disinfection agents, detergents and medical broad-spectrum antifungal dermatological products. At the same time, it is also an effective fungicide and an excellent common disinfectant for fruit trees, peanuts, wheat, vegetables and other crops. Its derivative product, zinc pyrithione, is also a commonly used fungicide for daily chemicals.
Chemische Eigenschaften
sodium pyrithione belongs to pyridine derivatives fungicide, appearance is yellow full light dumpling transparent liquid, melting point 250 ℃, slightly characteristic odor. Soluble in water and ethanol and other organic solvents, solubility (by mass fraction): water 53%, ethanol 19%, polyethylene glycol (PECG400) 12%. Best use pH range 7 to 10, mass fraction of 2% aqueous solution pH 8.0. Unstable to light, oxidizing agents and strong reducing agents. Non-ionic surfactants will deactivate it somewhat, and it can chelate with heavy metals.
Verwenden
sodium pyrithione is a preservative that is not commonly used because of some level of toxicity. It is prohibited in Canada, and it is on the eu Annex II list of substances that must not form part of a cosmetic product composition.
Verwenden
Sodium omadine is a bactericide for use in cooling fluids and short-term in-can preservation of vinyl acetate latex, paints, and synthetic-fiber lubricants; preservative for cosmetic rinse-off products.
Definition
Apparently exists in equilibrium with the -SH form. Forms chelates with iron, manganese, zinc, etc.
Application
2-Mercaptopyridine N-oxide sodium salt is one of the active components in paint, sealants, shampoo, adhesive and aerosol due to its anti-microbial activity. In biochemistry studies, it is utilized to transport zinc into cells. Further, it is used to form bidentate oxothiolane chelates with transition metals. It acts as a stabilizer and viscosity building provider in weak basic or neutral medium.
Trademarks
Sodium Omadine (Olin).
Allgemeine Beschreibung
2-Mercaptopyridine N-oxide acts as labelling agent during indium-111 labelling of human platelets. It acts as bioactive ligand and forms palladium and platinum complexes, which were tested as potential antitrypanosomal agents.
Biochem/physiol Actions
2-Mercaptopyridine N-oxide is a zinc ionophore that transports zinc into cells.
Sicherheitsprofil
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion, subcutaneous and parenteral routes. Used in preservation of cosmetics. When heated to decomposition it emits very toxic fumes of Na2O, NOx, and SOx. See also MERCAPTANS.
läuterung methode
When recrystallised from water, it assayed as 98.7% based on AgNO3 titration [Krivis et al. Anal Chem 35 966 1963; see also Krivis et al. Anal Chem 48 1001 1976, and Barton & Crich J Chem Soc, Perkin Trans 1 1603, 1613 1986]. [Beilstein 21/7 V 151.]
Mode of action
Pyrithione Sodium is the sodium salt form of pyrithione, a fungistatic and antimicrobial derivative of aspergillic acid. Although the exact mechanism of action remains to be fully elucidated, pyrithione sodium appears to interfere with membrane transport ultimately leading to a loss of metabolic control.

Sodium Pyrithione Upstream-Materialien And Downstream Produkte

Pyridin-2-thiol-1-oxid,Natriumsalz Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

3811-73-2, Sodium Pyrithione Verwandte Suche:

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