4-Nitrophenylboronic acid

Bezeichnung:4-Nitrophenylboronic acid

CAS-Nr24067-17-2

Englisch Name:4-Nitrophenylboronic acid

CBNumberCB3116883

SummenformelC6H6BNO4

Molgewicht166.93

MOL-Datei24067-17-2.mol

4-Nitrophenylboronic acid physikalisch-chemischer Eigenschaften

Schmelzpunkt	285-290°C (dec.)
Siedepunkt	373.7±44.0 °C(Predicted)
Dichte	1.40±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
Löslichkeit	DMF: 15 mg/ml; DMSO: 15 mg/ml; Ethanol: 15 mg/ml; Ethanol:PBS (pH 7.2) (1:5): 0.16 mg/ml
pka	7.04±0.10(Predicted)
Aggregatzustand	Crystalline Powder
Farbe	White to yellow
Wasserlöslichkeit	Slightly soluble in water.
InChIKey	NSFJAFZHYOAMHL-UHFFFAOYSA-N
CAS Datenbank	24067-17-2(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	22
S-Sätze:	26-36/37/39-24/25
WGK Germany	3
Hazard Note	Harmful
HS Code	29319090

Gefahreninformationscode (GHS)

4-Nitrophenylboronic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R22:Gesundheitsschädlich beim Verschlucken.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Beschreibung
4-Nitrobenzeneboronic acid is an arylboronic acid building block that has been used in the synthesis of phenols.
Chemische Eigenschaften
White to brown powder or crystal
Verwenden
Reagent used for
- Ligand-free palladium-catalyzed Suzuki-Miyaura cross-couplings
- Ruthenium catalyzed direct arylation of benzylic sp³ carbons of acyclic amines
- Diels-Alder or C-H activation reactions
- Regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulations
- N-arylation of phenylurea using copper acetylacetonate catalyst
- Environmentally benign one-pot synthesis through a double arylation process
- Copper-mediated cyanations
- copper-catalyzed arylations
- Regioselective glycosylations
- Suzuki couplings followed by arylations
- X-ray absorption on rhodium-grafted hydrotalcite catalyst for heterogeneous 1,4-addition reaction of organoboron reagents to electron deficient olefins
Reagent used in Preparation of
- Combretastatin analogs as potential antitumor agents
- Human immunodeficiency virus (HIV) protease inhibitors with antiviral activities against drug-resistant viruses
Verwenden
suzuki reaction
Verwenden
4-Nitrophenylboronic Acid is a useful synthetic intermediate. It is a reagent used for ligand-free palladium-catalyzed Suzuki-Miyaura cross-couplings, Ruthenium catalyzed direct arylation of benzylic sp3 carbons of acyclic amines and Diels-Alder or C-H activation reactions.

4-Nitrophenylboronic acid Upstream-Materialien And Downstream Produkte

4-Nitrophenylboronic acid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

24067-17-2, 4-Nitrophenylboronic acid Verwandte Suche:

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