Temocapril hydrochloride

Temocapril hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

• R-Sätze Betriebsanweisung:

  R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

• S-Sätze Betriebsanweisung:

  S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
  S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

• Beschreibung

  Temocapril is a novel ACE inhibitor marketed in Japan for the treatment of hypertension. Temocapril is three times more potent than enalapril by oral administration, and has a long duration of action. It is characterized by a rapid onset of action resulting from a fast conversion of temocapril to the active metabolite diacid. Unlike most ACE inhibitors which are excreted mainly through the kidneys, temocapril is excreted predominantly through the biliary route indicating that temocapril is especially useful for treating hypertensive patients with renal dysfunction. The potential usefulness of temocapril in the treatment of congestive heart failure has been reported.

• Chemische Eigenschaften

  White To Off-White Solid

• Originator

  Sankyo (Japan)

• Verwenden

  Angiotensin-converting enzyme (ACE) inhibitor. Hydrolyzed in vivo to the active diacid metabolite.

• Verwenden

  angiotensin-converting enzyme inhibitor (ACE-I)

• Definition

  ChEBI: Temocapril hydrochloride is a dipeptide.

• Trademarks

  Acecol

Temocapril hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global(179)Suppliers

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