Diethyl-4-nitrophenylphosphat

Bezeichnung:Diethyl-4-nitrophenylphosphat

CAS-Nr311-45-5

Englisch Name:PARAOXON

CBNumberCB2463711

SummenformelC10H14NO6P

Molgewicht275.2

MOL-Datei311-45-5.mol

Synonyma

Diethyl-4-nitrophenylphosphat

Diethyl-4-nitrophenylphosphat physikalisch-chemischer Eigenschaften

Schmelzpunkt	300°C
Siedepunkt	169-170°C
Dichte	1.274 g/mL at 25 °C(lit.)
Brechungsindex	n20/D 1.51(lit.)
storage temp.	2-8°C
Löslichkeit	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Aggregatzustand	oil
Farbe	yellow
Geruch (Odor)	slt odor
Wasserlöslichkeit	3.627g/L(20 ºC)
Merck	13,7102
BRN	1915526
Stabilität	Moisture Sensitive
CAS Datenbank	311-45-5
EPA chemische Informationen	Paraoxon (311-45-5)

Sicherheit

Kennzeichnung gefährlicher	T+,N
R-Sätze:	26/27/28-50
S-Sätze:	36/37/39-45-61
RIDADR	UN 2810 6.1/PG 1
WGK Germany	3
RTECS-Nr.	TC2275000
HazardClass	6.1(a)
PackingGroup	I
Giftige Stoffe Daten	311-45-5(Hazardous Substances Data)
Toxizität	LD50 orally in rats: 1.8 mg/kg (Pickering, Malone)

Gefahreninformationscode (GHS)

PARAOXON Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R26/27/28:Sehr giftig beim Einatmen, Verschlucken und Berührung mit der Haut.
S-Sätze Betriebsanweisung:
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
Paraoxon is an odorless, reddish-yellow oil. Fruity odor.
Chemische Eigenschaften
Oily Liquid
Verwenden
A cholinesterase inhibitor
Verwenden
Paraoxon-ethyl has been used as a substrate?in paraoxonase (PON) activity assay. It has also been used as a lipase inhibitor to study the effects of anacetrapib on homotypic transfer from high density lipoprotein?L3 (HDL3)?to?HDL2?in vivo.
Verwenden
Insecticide.
Definition
ChEBI: An aryl dialkyl phosphate where both the alkyl groups are ethyl and the aryl group is 4-nitrophenyl.
Synthesis Reference(s)
Tetrahedron Letters, 31, p. 3359, 1990 DOI: 10.1016/S0040-4039(00)89065-6
Allgemeine Beschreibung
Reddish-yellow oily liquid with a faint fruity odor.
Reaktivität anzeigen
Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Brandgefahr
Flash point data for PARAOXON are not available; however, PARAOXON is probably combustible.
Biochem/physiol Actions
Potent irreversible acetylcholinesterase inhibitor
Sicherheitsprofil
A deadly poison by ingestion,intraperitoneal, intravenous, subcutaneous, intramuscular,and parenteral routes. Mutation data reported. Humansystemic effects: coma, convulsions, miosis. Acholinesterase inhibitor. An insecticide. When heated todecompos
mögliche Exposition
An organophosphate insecticide. Has been used as a medication.
Versand/Shipping
UN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
Inkompatibilitäten
Keep away from alkaline materials and strong oxidizers. Contact with oxidizers can cause the release of toxic oxides of phosphorus. May react violently with antimony(V) pentafluoride. Incompatible with lead diacetate, magnesium, silver nitrate. In the presence of strong reducing agents such as hydrides, organophosphates form highly toxic and flammable phosphine gas.
Waste disposal
In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

PARAOXON Upstream-Materialien And Downstream Produkte

311-45-5, PARAOXON Verwandte Suche:

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