4-(4-Nitrophenyl)morpholine Struktur

4-(4-Nitrophenyl)morpholin

Bezeichnung:4-(4-Nitrophenyl)morpholin

CAS-Nr10389-51-2

Englisch Name:4-(4-Nitrophenyl)morpholine

CBNumberCB2178277

SummenformelC10H12N2O3

Molgewicht208.21

MOL-Datei10389-51-2.mol

Synonyma

4-(4-Nitrophenyl)morpholin

4-(4-Nitrophenyl)morpholin physikalisch-chemischer Eigenschaften

Schmelzpunkt	152 °C
Siedepunkt	386.2±37.0 °C(Predicted)
Dichte	1.265±0.06 g/cm3(Predicted)
RTECS-Nr.	QE7405000
storage temp.	Storage temp. 2-8°C
Löslichkeit	soluble in Dimethylformamide
pka	0.81±0.40(Predicted)
Aggregatzustand	powder to crystal
Farbe	Light yellow to Yellow to Orange
maximale Wellenlänge (λmax)	375nm(Dioxane)(lit.)
InChI	InChI=1S/C10H12N2O3/c13-12(14)10-3-1-9(2-4-10)11-5-7-15-8-6-11/h1-4H,5-8H2
InChIKey	IAJDSUYFELYZCS-UHFFFAOYSA-N
SMILES	N1(C2=CC=C([N+]([O-])=O)C=C2)CCOCC1
CAS Datenbank	10389-51-2(CAS DataBase Reference)
EPA chemische Informationen	Morpholine, 4-(4-nitrophenyl)- (10389-51-2)

Sicherheit

R-Sätze:	40-42/43-63
S-Sätze:	26-36
RIDADR	1662
TSCA	TSCA listed
HS Code	2934999090

Gefahreninformationscode (GHS)

4-(4-Nitrophenyl)morpholine Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R40:Verdacht auf krebserzeugende Wirkung.
R42/43:Sensibilisierung durch Einatmen und Hautkontakt möglich.
R63:Kann das Kind im Mutterleib möglicherweise schädigen.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Synthesis Reference(s)
Synthesis, p. 1145, 1990 DOI: 10.1055/s-1990-27118
Synthese

110-91-8

636-98-6

10389-51-2

GENERAL METHODS: Aryl halides (1.0 mmol), morpholine (1 mmol), sodium tert-butoxide (2 mmol) and 0.2 mol% of Pd/Nf-G catalyst were sequentially added to 1 mL of dimethyl sulfoxide (DMSO). The reaction mixture was stirred at 110 °C for 12 h. The reaction process was monitored by gas chromatography (GC). Upon completion of the reaction, the mixture was cooled to room temperature and extracted with ethyl acetate. The catalyst was recovered by simple filtration and subsequently washed with ethanol, dried and stored for subsequent use. The crude product was purified by column chromatography with the eluent being a mixed petroleum ether/ethyl acetate solvent. The recovered catalyst was reused in subsequent recyclability studies. The conversion of the reactants was determined by gas chromatography (GC).
Einzelnachweise
[1] Bulletin of the Chemical Society of Japan, 1991, vol. 64, # 1, p. 42 - 49
[2] Applied Organometallic Chemistry, 2013, vol. 27, # 12, p. 704 - 706
[3] RSC Advances, 2014, vol. 4, # 96, p. 53387 - 53396
[4] Tetrahedron Letters, 2015, vol. 56, # 30, p. 4463 - 4467
[5] Tetrahedron Letters, 2016, vol. 57, # 14, p. 1532 - 1536

4-(4-Nitrophenyl)morpholine Upstream-Materialien And Downstream Produkte

4-(4-Nitrophenyl)morpholin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

10389-51-2, 4-(4-Nitrophenyl)morpholine Verwandte Suche:

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