Tributylcitrat

Bezeichnung:Tributylcitrat

CAS-Nr77-94-1

Englisch Name:Tributyl citrate

CBNumberCB2299345

SummenformelC18H32O7

Molgewicht360.44

MOL-Datei77-94-1.mol

Synonyma

Tributylcitrat

Tributylcitrat physikalisch-chemischer Eigenschaften

Schmelzpunkt	≥300 °C(lit.)
Siedepunkt	234 °C (17 mmHg)
Dichte	1.043 g/mL at 20 °C (lit.)
Pour Point	-62
Brechungsindex	n20/D 1.445
Flammpunkt	300 °C
storage temp.	Store below +30°C.
Löslichkeit	Miscible with acetone, ethanol, and vegetable oil; practically insoluble in water.
pka	11.30±0.29(Predicted)
Aggregatzustand	Liquid
Farbe	Clear
Geruch (Odor)	odorless
Wasserlöslichkeit	insoluble
Merck	14,1564
BRN	1806072
InChIKey	ZFOZVQLOBQUTQQ-UHFFFAOYSA-N
LogP	4.324 (est)
CAS Datenbank	77-94-1(CAS DataBase Reference)
NIST chemische Informationen	Butyl citrate(77-94-1)
EPA chemische Informationen	1,2,3-Propanetricarboxylic acid, 2-hydroxy-, tributyl ester (77-94-1)

Sicherheit

Kennzeichnung gefährlicher	T
R-Sätze:	25
S-Sätze:	26-36/37/39-45-24/25
RIDADR	UN 2811 6.1/PG 2
WGK Germany	3
RTECS-Nr.	TZ8608000
TSCA	Yes
HS Code	29181500

Gefahreninformationscode (GHS)

Tributyl citrate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R25:Giftig beim Verschlucken.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
Colorless or pale-yellow, stable, odorless, nonvolatile liquid. Practically insoluble in water. Combustible.
Chemische Eigenschaften
Tributyl citrate is a clear, odorless, practically colorless, oily liquid.
Verwenden
Tributyl Citrate, is a non-phthalate plasticizer, that can be used for the preparation of resins. It can also used for the synthesis of Acetyl Tributyl Cirate, a valuable biodegradable plasticizer of low toxicity, found in nail polish and other cosmetics.
Verwenden
Tributyl citrate can be used:
- To incorporate in zein film to enhance its mechanical properties for industrial processing.
- As a plasticizer to improve the ductile properties of poly(lactide) polymers.
Verwenden
Plasticizer and solvent for nitrocellulose lacquers; in polishes, inks and similar Preparations; also as anti-foam agent.
Definition
ChEBI: Tributyl citrate is a carbonyl compound.
Vorbereitung Methode
Tributyl citrate is prepared by the esterification of citric acid with butanol.
Allgemeine Beschreibung
Tributyl citrate is an ester of citric acid. It is used to plasticize polymers for coating solid drug dosage forms, tablets and capsules.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards.
Pharmazeutische Anwendungen
Tributyl citrate is used to plasticize polymers in formulated pharmaceutical coatings. The coating applications include capsules, tablets, beads, and granules for taste masking, immediate release, sustained-release, and enteric formulations.
Sicherheit(Safety)
Tributyl citrate is used in oral pharmaceutical formulations. It is generally regarded as an essentially nontoxic and nonirritating material. However, ingestion of large quantities may be harmful.
LD50 (cat, oral): >50 mL/kg
LD50 (mouse, IP): 2.9 g/kg
LD50 (rat, oral): >30 mL/kg
Lager
Tributyl citrate should be stored in well-closed containers in a cool, dry location at temperatures not exceeding 38℃. When stored in accordance with these conditions, tributyl citrate is a stable material.
Inkompatibilitäten
Tributyl citrate is incompatible with strong alkalis and oxidizing materials.
Regulatory Status
Approved in the USA for indirect food contact in food films. Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Tributyl citrate Upstream-Materialien And Downstream Produkte

Tributylcitrat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

77-94-1, Tributyl citrate Verwandte Suche:

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