Bambermycin

Bezeichnung:Bambermycin

CAS-Nr11015-37-5

Englisch Name:Flavomycin

CBNumberCB2135441

SummenformelC69H107N4O35P

Molgewicht1583.57

MOL-Datei11015-37-5.mol

Synonyma

Bambermycin

Bambermycin physikalisch-chemischer Eigenschaften

Schmelzpunkt	>150° (dec.)
storage temp.	0-6°C
Löslichkeit	Water (Slightly)
Aggregatzustand	Solid
Farbe	Dark Brown
InChIKey	PERZMHJGZKHNGU-XIGAONJHSA-N
LogP	1.983 (est)
CAS Datenbank	11015-37-5
EPA chemische Informationen	Bambermycin (11015-37-5)

Sicherheit

R-Sätze:	53
RIDADR	UN 3077 9 / PGIII
WGK Germany	1
RTECS-Nr.	QA3020000
Toxizität	LD50 in mice (mg/kg): >2000 orally, s.c. and i.p.; 1400 i.v. (Lindner, Wallhuser)

Gefahreninformationscode (GHS)

Flavomycin Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung
Moenomycin complex is a mixture of moenomycins A, A₁₂, C₁, C₃ and C₄, which are antibiotics isolated from several strains of Streptomyces that directly inhibit bacterial peptidoglycan glycosyltransferases. The minimal inhibitory concentration of moenomycin A against various Gram-positive bacteria ranges from 1-100 nM.
Verwenden
Moenomycin complex is a mixture of five major components, A, A12, C1, C3 and C4, isolated from several strains of Streptomyces in the 1960s. Moenomycins are high molecular weight phosphoglycolipids with potent antibiotic activity used in animal health. Moenomycins are the only antibiotic known to selectively inhibit the transglycosylation step catalysed by penicillin-binding protein 1b.
Verwenden
Moenomycin complex is an antibiotic and selective inhibitor of the transglycosylation step. Flavomycin (bambermycins) is an antibiotic complex obtained from Streptomyces bambergiensis containing mainly Moenomycins A and C. They are used as feed additives and growth promoters for swine, poultry and cattle.
Definition
ChEBI: A glycophospholipid antibiotic compound with the lipid portion conjugated to a pentasaccharide fraction via a phosphate linkage.
Trademarks
Flavomycin (Hoechst-Roussel).
Allgemeine Beschreibung
Flavophospholipol, formerly called moenomycin, was found in the culture broth of Streptomyces bambergiensis by Hoechst in 1955. This drug is called bambermycin by INN and in the United States. It shows strong activity against gram-positive bacteria and weak activity against gram-negative bacteria. Flavophospholipol has been used as a feed additive for growth promotion in poultry.
Sicherheitsprofil
Poison by intravenous route. Moderately toxic by subcutaneous route.

Flavomycin Upstream-Materialien And Downstream Produkte

Bambermycin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

11015-37-5, Flavomycin Verwandte Suche:

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