Indole-5-carboxylic acid Struktur

Indol-5-carbonsure

Bezeichnung:Indol-5-carbonsure

CAS-Nr1670-81-1

Englisch Name:Indole-5-carboxylic acid

CBNumberCB0736428

SummenformelC9H7NO2

Molgewicht161.16

MOL-Datei1670-81-1.mol

Synonyma

Indol-5-carbonsure

Indol-5-carbonsure physikalisch-chemischer Eigenschaften

Schmelzpunkt	211-213 °C (lit.)
Siedepunkt	287.44°C (rough estimate)
Dichte	1.2480 (rough estimate)
Brechungsindex	1.5050 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit	Soluble in ethanol (50 mg/ml), dimethyl sulfoxide and methanol.
pka	4.40±0.30(Predicted)
Aggregatzustand	Powder
Farbe	Light beige to yellow
BRN	124391
InChIKey	IENZCGNHSIMFJE-UHFFFAOYSA-N
CAS Datenbank	1670-81-1(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	36/37/38-21/22
S-Sätze:	22-24/25-36/37/39-26
WGK Germany	3
HazardClass	IRRITANT
HS Code	29339990

Gefahreninformationscode (GHS)

Indole-5-carboxylic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R21/22:Gesundheitsschädlich bei Berührung mit der Haut und beim Verschlucken.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
light beige to yellow powder
Verwenden
Indole-5-carboxylic acid is the suitable reagent used to study the intramolecular excited state proton transfer in indole-2-carboxylic acid and indole-5-carboxylic acid in various solvents in acidic, basic, and neutral media by steady state and time resolved fluorescence spectroscopy. It may be used in the electrochemical synthesis of poly(indole-5-carboxylic acid) (PICA) films.
Verwenden
Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators 1 Reactant for preparation of indolyl-quinolines via metal- and solvent-free autoxidative coupling reaction 2 Reactant for preparation of anthranilic acids using bromamine-B oxidant and palladium chloride catalyst 3 Reactant for synthesis of indirubin derivatives 4 Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway 5 Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity.
Verwenden
Indole-5-carboxylic acid is the suitable reagent used to study the intermolecular excited state proton transfer in indole-2-carboxylic acid and indole-5-carboxylic acid in various solvents in acidic, basic, and neutral media by steady state and time resolved fluorescence spectroscopy. It may be used in the electrochemical synthesis of poly(indole-5-carboxylic acid) (PICA) films. Also used as reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators, synthesis of indirubin derivatives and amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway.
Definition
ChEBI: Indole-5-carboxylic acid is an indolecarboxylic acid in which the carboxy group is the only substituent and is located at position 5. It has a role as a plant metabolite.
Allgemeine Beschreibung
Indole-5-carboxylic acid is an indole derivative. On electropolymerization, it affords electroactive polymer film of poly(indole-5-carboxylic-acid). Different concentrations of indole-5-carboxylic acid in sulfuric acid solution has been investigated for the preventive action against mild steel corrosion. On electropolymerization it affords a trimeric product. Characterization studies of the trimeric product by ¹H NMR and various one- and two-dimensional NMR techniques have been reported.

Indole-5-carboxylic acid Upstream-Materialien And Downstream Produkte

Indol-5-carbonsure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

1670-81-1, Indole-5-carboxylic acid Verwandte Suche:

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