Serotonin hydrochloride

Bezeichnung:Serotonin hydrochloride

CAS-Nr153-98-0

Englisch Name:Serotonin hydrochloride

CBNumberCB0245131

SummenformelC10H13ClN2O

Molgewicht212.68

MOL-Datei153-98-0.mol

Serotonin hydrochloride physikalisch-chemischer Eigenschaften

Schmelzpunkt	149-154 °C(lit.)
storage temp.	2-8°C
Löslichkeit	H₂O: 17 mg/mL
Aggregatzustand	powder
Farbe	white to off-white
Wasserlöslichkeit	soluble
Sensitive	Light Sensitive & Hygroscopic
Merck	14,8462
BRN	3570963
Stabilität	Stable, but light sensitive and hygroscopic. Incompatible with strong oxidizing agents.
InChIKey	MDIGAZPGKJFIAH-UHFFFAOYSA-N
CAS Datenbank	153-98-0(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi,Hazard
R-Sätze:	20/21/22-36/37/38
S-Sätze:	22-26-36
RIDADR	UN2811
WGK Germany	3
RTECS-Nr.	NM2571000
F	3-8-10
HazardClass	6.1
PackingGroup	III
HS Code	29339900

Gefahreninformationscode (GHS)

Serotonin hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Chemische Eigenschaften
white to cream powder
Verwenden
Serotonin hydrochloride is used as a neurotransmitter and function as an endogenous serotonin receptor agonist in various biochemical processes. It is an active component, which is used to regulate the mood, emesis, cognition and appetite in vivo.
Verwenden
Serotonin is a monoamine neurotransmitter that is biochemically derived from tryptophan and produced in serotonergic neurons in the central nervous system and in enterochromaffin cells in the gastrointestinal tract. Serotonin is important in the regulation of mood, sleep, vomiting, sexuality, and appetite. Low levels of serotonin are associated with several disorders, including depression, migraines, bipolar disorder, and anxiety. Its actions are terminated primarily via uptake of serotonin from the synapse. Serotonin reuptake can be inhibited with MDMA, cocaine, tricyclic antidepressants, and selective serotonin reuptake inhibitors.[Cayman Chemical]
Verwenden
Neurotransmitter;5-HT agonist
Verwenden
Serotonin is a monoamine neurotransmitter.
Verwenden
A neurotransmitter.
Definition
ChEBI: Serotonin hydrochloride is a member of tryptamines. It is functionally related to a serotonin.
Biologische Aktivität
Endogenous agonist at 5-HT receptors and endogenous substrate for 5-HT transporters. Neurotransmitter that has roles in regulation of mood, emesis, sexuality, sleep and appetite in vivo .
Biochem/physiol Actions
Neurotransmitter.
Lager
Store at -20°C
läuterung methode
5-HT is purified by recrystallisation from EtOH/Et2O or Et2O to give the hygroscopic salt. Store it in the dark as it is light sensitive. The free base has m 84-86o (from Et2O). The 5-benzyloxy derivative has m 84-86o (from Et2O). [Ek & Witkop J Am Chem Soc 76 5579 1954, Hamlin & Fischer J Am Chem Soc 73 5007 1951.] The picrate 1H2O has m 196-197.5o (dec with sintering at 160-165o) after crystallisation from Et2O. Serotonin is a natural neurotransmitter [Chuang Life Sci 41 1051 1987]. [Beilstein 22/12 V 16.]

Serotonin hydrochloride Upstream-Materialien And Downstream Produkte

Serotonin hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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