7-Nitroindole Struktur

7-Nitroindole

Bezeichnung:7-Nitroindole

CAS-Nr6960-42-5

Englisch Name:7-Nitroindole

CBNumberCB0215228

SummenformelC8H6N2O2

Molgewicht162.15

MOL-Datei6960-42-5.mol

7-Nitroindole physikalisch-chemischer Eigenschaften

Schmelzpunkt	94-98 °C (lit.)
Siedepunkt	288.82°C (rough estimate)
Dichte	1.3264 (rough estimate)
Brechungsindex	1.5770 (estimate)
storage temp.	Sealed in dry,Room Temperature
Aggregatzustand	powder to crystal
pka	13.96±0.30(Predicted)
Farbe	Light yellow to Yellow to Orange
Wasserlöslichkeit	slightly soluble
BRN	130874
CAS Datenbank	6960-42-5(CAS DataBase Reference)

Sicherheit

Kennzeichnung gefährlicher	Xn,Xi
R-Sätze:	68
S-Sätze:	36/37-45
WGK Germany	3
RTECS-Nr.	NM1169000
Hazard Note	Irritant
HazardClass	IRRITANT-HARMFUL
HS Code	29339900

Gefahreninformationscode (GHS)

7-Nitroindole Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R68:Irreversibler Schaden möglich.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
Chemische Eigenschaften
yellow crystalline powder
Verwenden
Reactant for preparation of:
- Protein kinase inhibitors
- Potential fructose 1,6-bisphosphatase inhibitors
- Factor Xa inhibitors
- Antagonist of the mineralocorticoid receptor
- Antitumor sulfonamides
- Inosine monophosphate dehydrogenase (IMPDH) inhibitors
- Subtype-selective cyclooxygenase (COX) inhibitors
- Thrombin protease-activated receptor (PAR-1) ligands
Verwenden
7-Nitroindole is a useful reactant for the preparation of various compounds and inhibitors.
Verwenden
7-Nitroindole is a reagent used in chemical synthesis. It has been used in the synthesis of protein kinase and inosine monophosphate inhibitors, beta3 agonists and CCK-1 receptor modulators. 7-Nitroindole has also been used as a photochemical precursor of the 2'-deoxyribonolactone analog.
Application
Reactant for preparation of:
Protein kinase inhibitors
Potential fructose 1,6-bisphosphatase inhibitors
Factor Xa inhibitors
Antagonist of the mineralocorticoid receptor
Antitumor sulfonamides
Inosine monophosphate dehydrogenase (IMPDH) inhibitors
Subtype-selective cyclooxygenase (COX) inhibitors
Thrombin protease-activated receptor (PAR-1) ligands
Synthesis Reference(s)
Canadian Journal of Chemistry, 42, p. 1235, 1964 DOI: 10.1139/v64-189

7-Nitroindole Upstream-Materialien And Downstream Produkte

7-Nitroindole Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

6960-42-5, 7-Nitroindole Verwandte Suche:

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