ChemicalBook CAS数据库列表 非诺特罗
非诺特罗
- CAS号:13392-18-2
- 英文名:Fenoterol
- 中文名:非诺特罗
- CBNumber:CB6215967
- 分子式:C17H21NO4
- 分子量:303.35
- MOL File:13392-18-2.mol
非诺特罗化学性质
- 熔点 :181-183°C
- 沸点 :566.0±45.0 °C(Predicted)
- 密度 :1.289±0.06 g/cm3(Predicted)
- 储存条件 :Store at -20°C
- 酸度系数(pKa) :pKa 8.5 (Uncertain);10.0 (Uncertain)
- CAS 数据库 :13392-18-2(CAS DataBase Reference)
非诺特罗性质、用途与生产工艺
- 生物活性 Fenoterol (Phenoterol) 是β2 adrenoreceptor激动剂，具有支气管扩张活性。
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靶点
Target Value β2 adrenoreceptor
() -
体外研究
Fenoterol (1 μM; pre-incubated 30 minutes) treatment reduces AICAR-induced AMPK activation, NF-κB activation and TNF-α release, and also significantly downregulates the elevated phosphorylation levels of AMPK.
Fenoterol inhibits lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells.
Fenoterol is also a potent exosome biogenesis and/or secretion activator in PC cells.Western Blot Analysis
Cell Line: THP-1 cells stimulated with AICAR Concentration: 1 μM Incubation Time: Pre-incubated 30 minutes Result: Significantly downregulated the elevated phosphorylation levels of AMPK. -
体内研究
Fenoterol (0.7 mg/kg; intraperitoneal injection; twice a day; for 3 weeks) treatment suppresses mechanical allodynia during chronic treatment.
Animal Model: Male C57BL/6J mice (6 weeks old) with neuropathy Dosage: 0.7 mg/kg Administration: Intraperitoneal injection; twice a day; for 3 weeks Result: Alleviated neuropathic allodynia during chronic treatment.
非诺特罗上下游产品信息
上游原料
下游产品
非诺特罗 试剂级价格
- 更新日期：2024/04/30
- 产品编号：HY-B0976
- 产品名称：Fenoterol
- CAS编号：
- 包装：10 mg
- 价格：750元
- 更新日期：2024/04/30
- 产品编号：S5769
- 产品名称：非诺特罗 Fenoterol
- CAS编号：13392-18-2
- 包装：5mg
- 价格：795.25元
非诺特罗生产厂家
- 公司名称：Taj Mahal Vision Chemicals Private Limited
- 联系电话：--
- 电子邮件：
- 国家：印度
- 产品数：206
- 优势度：58
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