508-99-6
基本信息
化合物 T19358
氢化可的松环戊丙酸酯
Hydrocortisone cipionate
HYDROCORTISONE CYPIONATE
Hydrocortisone 21-cypionate
HYDROCORTISONE CYPIONATE (200 MG)
Hydrocortisone Cypionate (1318000)
21-(3-Cyclopentyl-1-oxopropoxy)-11β,17α-dihydroxypregn-4-ene-3,20-dione
11beta,17,21-trihydroxypregn-4-ene-3,20-dione 21-cyclopentanepropionate
(11β)-21-(3-Cyclopentyl-1-oxopropoxy)-11,17-dihydroxypregn-4-ene-3,20-dione
Pregn-4-ene-3,20-dione, 21-(3-cyclopentyl-1-oxopropoxy)-11,17-dihydroxy-, (11β)-
物理化学性质
| 沸点 | 645.0±55.0 °C(Predicted) |
| 密度 | 1.22±0.1 g/cm3(Predicted) |
| 储存条件 | -20°C储存 |
| 溶解度 | DMSO: 125 mg/mL (256.86 mM) |
| 酸度系数(pKa) | 12.33±0.70(Predicted) |
| 形态 | Solid |
| 颜色 | White to off-white |
氢化可的松环戊丙酸酯价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/08/19 | HY-U00089 | 氢化可的松环戊丙酸酯 Hydrocortisone cypionate | 508-99-6 | 1mg | 800元 |
| 2024/08/19 | HY-U00089 | 氢化可的松环戊丙酸酯 Hydrocortisone cypionate | 508-99-6 | 5mg | 1800元 |
| 2024/08/19 | HY-U00089 | 氢化可的松环戊丙酸酯 Hydrocortisone cypionate | 508-99-6 | 10mM * 1mLin DMSO | 1927元 |
常见问题列表
Hydrocortisone (50 nM) shows a dose-dependent down-regulation of GR transcript in hCMEC/D3 cells. Hydrocortisone supplementation of the serum-reduced cell differentiation medium leads to a significant increase in TER across the hCMEC/D3 monolayer. Hydrocortisone-treated Dendritic cells (DCs) show a decreased expression of MHC II molecules, the costimulatory molecule CD86, and the DC-specific marker CD83, as well as a strongly reduced IL-12 secretion. Hydrocortisone-treated DCs inhibit production of IFN-γ but induce an increased release of IL-4 and no change in IL-5. Hydrocortisone reduces postischemic oxidative stress, perfusion pressure, and transudate formation. Hydrocortisone inhibits postischemic shedding of syndecan-1, heparan sulfate, and hyaluronan as is release of histamine from resident mast cells.