402713-81-9
物理化学性质
| 储存条件 | room temp |
| 储存条件 | room temp |
| 溶解度 | H2O：可溶15mg/mL，澄清 |
| 形态 | 粉末 |
| 颜色 | 白色至米色 |
安全数据
| 危险性符号(GHS) |  GHS07 |
| 警示词 | 警告 |
| 危险性描述 | H315-H319-H335 |
| 防范说明 | P261-P305+P351+P338 |
| 危险品标志 | Xi |
| 危险类别码 | 36/37/38 |
| 安全说明 | 26 |
| WGK Germany | 3 |
常见问题列表
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5-HT 6 Receptor
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Compare with the control vehicle SB-399885 hydrochloride 10 mg/kg significantly increases wakefulness (W) (F (3,15) =3.32, P<0.05) while slow wave sleep (SWS), rapid-eye-movement sleep (REMS) and the number of REM periods are reduced (F (3,15) =4.0, P<0.01; F (3,15) =3.14, P<0.05 and F (3,15) =2.62, P<0.05, respectively). Analysis of sleep variables in 2-h blocks shows that SB-399885 hydrochloride 10 mg/kg increases W (F (3,15) =5.48, P<0.01) and reduces SWS (F (3,15) =5.42, P<0.01) and REMS (F (3,15) = 4.05, P<0.01) during the first 2-h period. SB-399885 hydrochloride 5 and 10 mg/kg augment light sleep over the first (F (3,15) =3.46,P<0.01 and F (3,15) = 3.65, P<0.01, respectively) and the second (F (3,15) =3.23, P<0.05 and F (3,15) =3.08, P<0.05, respectively) 2-h recording periods. SB-399885 hydrochloride 10 mg/kg significantly increases REMS latency (F (3,15) =3.60, P<0.01) and reduces the number of REM periods during the first 2-h of recording (F (3,15) =3.88, P<0.01).