304-55-2
基本信息
二巯基丁二酸
二巯丁二酸
间-2,3-二巯基丁二酸
MESO-2,3-二巯基丁二酸
2,3-DITHIO-MESO-TARTARIC ACID
DMSA
MESO-2,3-DIMERCAPTOSUCCINIC ACID
SUCCIMER
(r*,s*)-2,3-dimercaptobutanedioicacid
2,3-dimercapto-,(r*,s*)-butanedioicaci
2,3-dimercapto-,(theta,s)-butanedioicaci
3-dimercapto-meso-succinicaci
chemet
dim-sa
meso-2,3-dithiosuccinicacid
meso-dimercaptosuccinicacid
ro1-7977
MESO-2,3-DIMERCAPTOSUCCINIC ACIDF&D VERS ION
MESO-2,3-DIMERCAPTO SUCCINIC ACID ENTERPRISE STANDARD =98.5%
DimercaptosuccinicAcid(Dmsa)
2,3-Dimercaptosuccinic
2,3-DIMERCAPTOSUCCINICACIDMESO
MESO-DMSA
物理化学性质
外观性状 | 白色结晶性粉末。熔点196-198℃(分解)。易溶于碱溶液,微溶于甲醇,不溶于水。具有巯基化合物的特臭,在空气中逐渐氧化。 |
溶解性 | 不溶于水,易溶于碱性溶液,微溶于甲醇。 |
熔点 | 196-198 °C (dec.)(lit.) |
沸点 | 285.62°C (rough estimate) |
密度 | 1.439 (estimate) |
折射率 | 1.5220 (estimate) |
储存条件 | −20°C |
溶解度 | DMSO(微溶)、甲醇(微溶,加热) |
酸度系数(pKa) | pK1:2.71;pK2:3.48;pK3:8.89(SH);pK4:10.79(SH) (25°C) |
形态 | 粉末 |
颜色 | 白色至灰白色 |
水溶解性 | Soluble in water, and ethanol (25 mg/ml, results in colorless to light yellow, clear). |
Merck | 14,8865 |
BRN | 1725150 |
稳定性 | 稳定的。易燃。与强氧化剂不相容。 |
InChIKey | ACTRVOBWPAIOHC-XIXRPRMCSA-N |
CAS 数据库 | 304-55-2(CAS DataBase Reference) |
EPA化学物质信息 | Butanedioic acid, 2,3-dimercapto-, (2R,3S)-rel- (304-55-2) |
安全数据
危险性符号(GHS) | GHS07,GHS08 |
警示词 | 警告 |
危险性描述 | H315-H319-H335-H361 |
防范说明 | P201-P261-P280-P305+P351+P338-P405-P501a |
危险品标志 | Xi |
危险类别码 | R36/37/38 |
安全说明 | S24/25 |
WGK Germany | 2 |
RTECS号 | WM7650000 |
F | 10-23 |
TSCA | Yes |
海关编码 | 29309090 |
毒害物质数据 | 304-55-2(Hazardous Substances Data) |
毒性 | LD50 i.p. in mice: >3000 mg/kg (Friedheim, Corvi) |
制备方法
常见问题列表
Succimer is a widely used chelating agent for the treatment of Pb poisoning. Red blood cells (RBCs) from lead exposed animals treated with NAC or Succimer are shown to have significantly higher glutathione (GSH) levels and diminished malondialdehyde (MDA) levels when compare to the lead group. Succimer administration also results in decreased glucose 6-phosphate dehydrogenase (G6PD) activity in RBCs from lead exposed animals. Succimer treatment produces a significant reduction in blood lead levels for both lead exposure conditions: the High Pb-succ group has blood lead levels that are 27% of the blood lead levels of the High Pb group at the end of treatment. Succimer is effective in substantially reducing brain lead, as brain lead levels in the High Pb-succ group are 37% of levels in the High Pb group.
知名试剂公司产品信息
2,3-二巯基丁二酸价格(试剂级)
报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
2024/11/08 | A17909 | 间-2,3-二巯基丁二酸, 97% meso-2,3-Dimercaptosuccinic acid, 97% | 304-55-2 | 1g | 250元 |
2024/11/08 | A17909 | 间-2,3-二巯基丁二酸, 97% meso-2,3-Dimercaptosuccinic acid, 97% | 304-55-2 | 5g | 897元 |
2024/11/08 | 22667 | 2,3-二巯基丁二酸 meso-2,3-Dimercaptosuccinic acid, 98%, Thermo Scientific Chemicals | 304-55-2 | 5g | 1645元 |