ChemicalBook CAS DataBase List 814-49-3

814-49-3

Name	Diethyl chlorophosphate
CAS	814-49-3
EINECS(EC#)	212-396-4
Molecular Formula	C4H10ClO3P
MDL Number	MFCD00009075
Molecular Weight	172.55
MOL File	814-49-3.mol

Synonyms

AURORA KA-1634 CHLOROPHOSPHORIC ACID DIETHYL ESTER DIETHYL CHLOROPHOSPHATE DIETHYL PHOSPHOROCHLORIDATE DIETHYL PHOSPHORYL CHLORIDE Phosphorochloridic acid diethyl ester ai3-18557[qr] Chlorodiethoxyphosphine oxide Chlorodiethylphosphate Diethoxyphosphorus oxychloride diethoxyphosphorusoxychloride diethoxyphosphorusoxychloride[qr] Diethoxyphosphoryl chloride Diethyl chloridophosphate Diethyl chlorophosphonate Diethyl phosphochloridate Diethyl phosphorochloride Diethylchlorfosfat diethylchlorfosfat(czech)[qr] Diethylchlorophosphidate

Chemical Properties

Appearance	clear colorless to light yellow liquid
Melting point	95-96 °C
Boiling point	60 °C2 mm Hg(lit.)
density	1.194 g/mL at 25 °C(lit.)
vapor density	5.94 (vs air)
vapor pressure	0.1 mm Hg ( 25 °C)
refractive index	n20/D 1.416(lit.)
Fp	142 °F
storage temp.	2-8°C
solubility	Chloroform (Sparingly)
form	Liquid
color	Clear colorless to light yellow
Water Solubility	Soluble in alcohol and chloroform. Slightly soluble in water.
Sensitive	Moisture Sensitive
BRN	471433
Stability:	Hygroscopic, Moisture Sensitive
InChI	1S/C4H10ClO3P/c1-3-7-9(5,6)8-4-2/h3-4H2,1-2H3
InChIKey	LGTLXDJOAJDFLR-UHFFFAOYSA-N
SMILES	CCOP(Cl)(=O)OCC
LogP	0.61
CAS DataBase Reference	814-49-3(CAS DataBase Reference)
NIST Chemistry Reference	Phosphorochloridic acid, diethyl ester(814-49-3)
EPA Substance Registry System	814-49-3(EPA Substance)

Safety Data

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H300+H310-H331
Precautionary statements	P262-P264-P280-P301+P310-P302+P352+P310-P304+P340+P311
Hazard Codes	T+
Risk Statements	R23:Toxic by inhalation. R27/28:Very Toxic in contact with skin and if swallowed . R33:Danger of cumulative effects. R26/27/28:Very Toxic by inhalation, in contact with skin and if swallowed . R34:Causes burns. less more
Safety Statements	S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . S38:In case of insufficient ventilation, wear suitable respiratory equipment . S7/9:Keep container tightly closed and in a well-ventilated place . less more
RIDADR	UN 2927 6.1/PG 1
WGK Germany	3
RTECS	TD1400000
F	10-19-21
TSCA	Yes
REACH Registrations	Active
HazardClass	6.1(a)
PackingGroup	II
HS Code	29199000
Storage Class	6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
Hazard Classifications	Acute Tox. 1 Dermal Acute Tox. 2 Oral Acute Tox. 3 Inhalation
Safety Profile	Deadly poison by skin contact. Poison by ingestion. A cholinesterase inhibitor. See also PARATHION. Trace HCl catalyzes a hazardous reaction during the preparation of diethyl phosphate from diethyl chlorophosphate. When heated to decomposition it emits very toxic fumes of Cl and POx. less more
Hazardous Substances Data	814-49-3(Hazardous Substances Data)

Raw materials And Preparation Products

Hazard Information

General Description

Clear liquid. This material is used as an intermediate in organic synthesis.

Reactivity Profile

Organophosphates, such as DIETHYL CHLOROPHOSPHATE, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Health Hazard

This material is a cholinesterase inhibitor. It has high oral and very high dermal toxicity. It is a skin irritant. It is also toxic by inhalation.

Fire Hazard

Emits very toxic fumes of chloride and phosphorus oxides when heated to decomposition.

Description

Diethyl chlorophosphate is a combustible,clear liquid with an unpleasant odor. Molecularweight=172.76; Boiling point=60℃ at 2.0 mmHg; 81℃at 6.0 mmHg. Freezing/Melting point=0℃. HazardIdentification (based on NFPA-704 M Rating System):Health 4, Flammability 2, Reactivity 2 . Reacts withwater.

Chemical Properties

clear colorless to light yellow liquid

Uses

A phosphorous halide used for biochemical research. Also used as an intermediate in organic synthesis.

Potential Exposure

This material may be used as an intermediate in the manufacture of pesticides and chemical warfare agents.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Speed in removing material from skinis of extreme importance. Shampoo hair promptly if contaminated. Seek medical attention immediately. If thischemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, includingresuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give conscious victims water or milk.Promote excretion by administering saline cathartic or sorbitol. Do not make an unconscious person vomit.

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, wellventilated area away from oxidizers and reducing agents.Where possible, automatically pump liquid from drums orother storage containers to process containers.

Shipping

Organophosphorus compound, toxic n.o.s.requires a label of “POISONOUS/TOXIC MATERIALS.”These materials fall in Hazard Class 6.1 and Packing GroupII.

Incompatibilities

Contact with oxidizers may cause therelease of phosphorous oxides. Contact with strong reducingagents, such as hydrides, may cause the formation of flammable and toxic phosphine gas. Strong oxidizers, bases.

Material Safety Data Sheet(MSDS)

Spectrum Detail

Well-known Reagent Company Product Information

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