81371-54-2

Lung carcinogenic model in ICR mice is induced by Urethane (HY-B1207) (600 mg/kg; i.p.; once weekly for 4 or 8 weeks), or in in macrophage-competent and macrophage-deleted mice is induced by LPS (HY-D1056) (2 mg/kg; intratracheal method) with 4 mg/mouse IEC (i.p.)^[1].
Momordicoside G (50 mg/kg; p.o.; once daily for 4 or 8 weeks) prevents urethane-induced lung injury and carcinoma lesions in mouse lung carcinogenic model^[1].
Momordicoside G (50 mg/kg; p.o.; once daily for 2 weeks) promotes lung injury repair in LPS-induced lung injury model^[1].