78491-02-8

Name Diazolidinylurea
CAS 78491-02-8
EINECS(EC#) 278-928-2
Molecular Formula C4H10N4O
MDL Number MFCD00079129
Molecular Weight 130.15
MOL File 78491-02-8.mol

Chemical Properties

Appearance white powder
Boiling point  421.04°C (rough estimate)
density  1.4734 (rough estimate)
vapor pressure  0Pa at 20℃
refractive index  1.6590 (estimate)
storage temp.  2-8°C
solubility  Water (Slightly)
form  Solid
pka 11.22±0.46(Predicted)
color  White to Off-White
Stability: Stable. Incompatible with strong oxidizing agents.
Water Solubility  1000g/L at 20℃
Merck  3000
Cosmetics Ingredients Functions PRESERVATIVE
Cosmetic Ingredient Review (CIR) Diazolidinyl Urea (78491-02-8)
InChI 1S/C8H14N4O7/c13-1-9-7(18)10(2-14)5-6(17)12(4-16)8(19)11(5)3-15/h5,13-16H,1-4H2,(H,9,18)
Contact allergens
Diazolidinyl urea, a formaldehyde releaser, is contained mainly in cosmetics and toiletries and can be found in barrier creams.
InChIKey SOROIESOUPGGFO-UHFFFAOYSA-N
SMILES OCNC(=O)N(CO)C1N(CO)C(=O)N(CO)C1=O
LogP 0.9 at 20℃
Uses
diazolidinyl urea is an antiseptic and deodorizer. It is also a broadspectrum preservative against bacteria and fungi. generally, it is used in concentrations of 0.03 to 0.3 percent. It has been found that diazolidinyl urea is a stronger sensitizer than imidazolidinyl urea for people sensitive or allergic to formaldehyde.
CAS DataBase Reference 78491-02-8(CAS DataBase Reference)
EPA Substance Registry System 78491-02-8(EPA Substance)

Safety Data

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313
Hazard Codes  Xi
Risk Statements 
R43:May cause sensitization by skin contact.
Safety Statements 
S36/37:Wear suitable protective clothing and gloves .
WGK Germany  2
RTECS  YS2717000
TSCA  TSCA listed
REACH Registrations Active
HS Code  29339900
Toxicity
LD50 orally in rats: 2.57 g/kg; dermally in rabbits: >2.0 g/kg (Berke, Rosen)

Hazard Information

Well-known Reagent Company Product Information

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