Description
Cef menoxime hydrochloride is a third generation cephalosporin antibiotic.
Structurally, it possesses the (1-methyl-lH-tetrazol-5-yl)thiomethyl moiety in
the 3-position; like several other compounds containing this structural element
(moxalactam, cefoperazone, cefamandol), bleeding linked to vitamin K interaction
has been reported. Cefmenoxime has activity similar to cefotiuime, ceftizoxime
and moxalactam against E.coli, C. diversus, Klebsiella, P. Mirabilis, Salmonella,
Shigella, Neiseria spp., S. pyogenes, S. Pneumoniae, and g. influenzae. It is
relatively ineffective against Pseudomonas and Bacteroidea.
Uses
A third generation cephalosporin antibiotic with strong antimicrobial activities against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella subgenus Branhamella catarrhalis that were 3 major aerobic bacteria from sinusitis.