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13392-28-4

Supplier Related Products Identification Chemical Properties Raw materials And Preparation Products Safety Data Questions And Answer

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Identification

Name
Rimantadine
CAS
13392-28-4
Synonyms
1-(1-ADAMANTYL)ETHYLAMINE
AKOS B022266
AKOS NCG1-0034
LEVOFLOXACIN HCL
LEVOFLOXACIN HYDROCHLORIDE
RIMANTADINE
1-(1-Adamantyl)ethanamine
1-Adamantanemethylamine, alpha-methyl-
alpha-Methyl-1-adamantanemethylamine
alpha-Methyladamantanemethylamine
Tricyclo(3.3.1.13,7)decane-1-methanamine, alpha-methyl-
Tricyclo[3,3,1,1(3,7)]decane-1-methanamine, alpha-methyl-
Levofloxacine Hydrochloride
Flunarizine hydrochloride cp2000,BP98
Rimantadine (base and/or unspecified salts)
1-Adamantanemethylamine
α-Methyl-1-adamantanemethanamine
Molecular Formula
C11H19N
MDL Number
MFCD03265511
Molecular Weight
165.28
MOL File
13392-28-4.mol

Chemical Properties

bp 
248°C
density 
1.033
Fp 
99°C
CAS DataBase Reference
13392-28-4(CAS DataBase Reference)
NIST Chemistry Reference
1-Adamantanemethylamine, «alpha»-methyl-(13392-28-4)

Raw materials And Preparation Products

Safety Data

Hazardous Substances Data
13392-28-4(Hazardous Substances Data)

Questions And Answer

Description
Rimantadine (Brand name: Flumadine) is a kind of RNA synthesis inhibitor that used as an orally administrated antiviral drug in the prophylaxis and for the treatment of influenza. It is capable of shortening the duration and alleviated the symptoms of influenza. However, it is now not recommended for the treatment of influenza any longer due to the emergence of resistance problem since 2009. Its mechanism of action is not fully understood. It is indicated that it take effects through inhibiting the viral replication through possibly inhibiting the uncoating process of the virus. The virus M2 protein (an ion channel) seems to play an important role in the susceptibility of influenza A virus to the treatment of Rimantadine.
References
https://www.drugbank.ca/drugs/DB00478
https://en.wikipedia.org/wiki/Rimantadine
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