73771-04-7

Topical anti-inflammatory agent. Glucocorticoid.

Prednicarbate is a potent topical antiinflammatory agent with minimal systemic effects. It is useful in the treatment of cutaneous inflammatory disorders such as eczema and psoriasis.

Prednicarbate is a synthetic corticosteroid and a derivative of prednisolone (Item No. 20866). It has anti-inflammatory activity comparable to that of desoximetasone in various murine models when administered topically but lacks activity when administered subcutaneously. Topical administration of prednicarbate (2 drops of a 0.1% solution per day) induces wound healing in hairless mice. Formulations containing prednicarbate have been used to treat chronic hand eczema.

White or almost white, crystalline powder.

Hoechst AG (W. Germany)

Topical anti-inflammatory agent. Glucocorticoid.
Prednicarbate (Dermatop E) is a synthetic nonfluorinated topical corticosteroid.

ChEBI: Prednicarbate is a corticosteroid hormone.

Prednicarbate (Dermatop E) is a synthetic nonfluorinated topical corticosteroid.

Dermatop (Sanofi Aventis).

Prednicarbate, 17-[(ethoxycarbonyl)oxy]-11β-hydroxy-21-(1-oxopropoxy)pregna-1,4-diene-3,20-dione, is a prednisolone derivative with a C21 propionateester and a C17 ethyl carbonate group. It is availablefor use only in a 0.1% topical cream. Prednicarbate is amedium-potency GC.