624-38-4

white to light yellow crystal powder

suzuki reaction

1,4-Diiodobenzene is obtained by diazotising p-iodoaniline followed by substitution. An alternative preparation method involves diazotising p-phenylenediamine hydrochloride, followed by substitution with potassium iodide.

Crystallise it from EtOH or boiling MeOH, then dry it in air. [Beilstein 5 IV 700.]

[1] JENS CARDINALE  Heinz H C  Johannes Ermert. Convenient preparation of (4-iodophenyl)aryliodonium salts[J]. Tetrahedron, 2012, 68 22: Pages 4112-4116. DOI:10.1016/j.tet.2012.03.113.
[2] ROEL S. SÁNCHEZ-CARRERA. Charge-Transport Properties of the 1,4-Diiodobenzene Crystal: A Quantum-Mechanical Study[J]. Chemistry of Materials, 2008, 20 18: 5832-5838. DOI:10.1021/cm801108c.
[3] DU ZONG-DA   Yang C X  Cui Yuan Yuan. Synthesis of silica amino-functionalized microporous organic network composites for efficient on-line solid phase extraction of trace phenols from water.[J]. Journal of Chromatography A, 2020, 1616: 460791. DOI:10.1016/j.chroma.2019.460791.