ChemicalBook CAS DataBase List 6184-17-4

6184-17-4

Name	RIBOFLAVIN-5'-PHOSPHATE SODIUM SALT DIHYDRATE
CAS	6184-17-4
EINECS(EC#)	204-988-6
Molecular Formula	C17H24N4NaO11P
MDL Number	MFCD00150993
Molecular Weight	514.36
MOL File	6184-17-4.mol

Synonyms

FLAVINE MONONUCLEOTIDE NA, DIHYDRATE FLAVINE MONONUCLEOTIDE SODIUM SALT DIHYDRATE FLAVINMONONUCLEOTIDE DIHYDRATE FLAVIN MONONUCLEOTIDE MONOSODIUM SALT DIHYDRATE FLAVIN MONONUCLEOTIDE SODIUM SALT DIHYDRATE FMM-NA 2H2O FMN FMN, DIHYDRATE FMN MONOSODIUM SALT DIHYDRATE FMN-NA DIHYDRATE FMN SODIUM SALT, DIHYDRATE RIBOFLAVIN 5'-MONOPHOSPHATE SODIUM SALT DIHYDRATE RIBOFLAVIN-5'-PHOSPHATE MONOSODIUM SALT DIHYDRATE RIBOFLAVIN 5'-PHOSPHATE SODIUM, DIHYDRATE RIBOFLAVIN-5'-PHOSPHATE SODIUM SALT DIHYDRATE RIBOFLAVINE 5'-PHOSPHATE MONOSODIUM SALT DIHYDRATE RIBOFLAVINE-5'-PHOSPHATE SODIUM SALT DIHYDRATE RIBOFLAVINE PHOSPHATE SODIUM SALT DIHYDRATE RIBOFLAVIN SODIUM PHOSPHATE SODIUM RIBOFLAVINE PHOSPHATE DIHYDRATE

Chemical Properties

Appearance	Yellowish crystalline powder
Melting point	>300°C
storage temp.	2-8°C
solubility	H₂O: 0.1 g/mL, clear, orange-yellow
form	powder
color	Orange to Dark Orange
Stability:	Stable. Incompatible with strong oxidizing agents.
Water Solubility	Soluble in water at 50mg/ml
Merck	14,8201
BRN	4106529
CAS DataBase Reference	6184-17-4(CAS DataBase Reference)

Safety Data

Safety Statements	S22:Do not breathe dust . S24/25:Avoid contact with skin and eyes . less more
WGK Germany	3
F	8
TSCA	Yes
HS Code	29362300

Hazard Information

Description

Riboflavin 5''-monophosphate (FMN) is a coenzyme that is tightly bound to enzymes catalyzing oxidation and reduction reactions in a variety of biosynthetic pathways. FMN also binds the FMN riboswitch (RFN element) on RNA to alter gene regulation. FMN is a substrate of FMN phosphohydrolases and is used to study their function.

Chemical Properties

Yellowish crystalline powder

Uses

Riboflavin 5′-monophosphate (FMN) is used as a prosthetic group by oxidoreductase (one and two electron transfer) enzymes such as NADH dehydrogenases, nitric oxide synthases, and nitrilotriacetate monooxygenases. Riboflavin 5′-monophosphate is used as a substrate to study the specificity and kinetics of FMN phosphohydrolases. FMN is used to study molecular sensing based gene regulation by riboswitches.

Uses

Riboflavin 5''-(Dihydrogen Phosphate) Monosodium Salt Dihydrate is a phosphated nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, leafy vegetables. Richest natural source is yeast. Minute amounts present in all plant and animal cells. Vitamin (enzyme cofactor).

General Description

Riboflavin 5′-monophosphate (FMN) is highly soluble in water. Flavins are considered as blue-light absorbing dyes.

Biochem/physiol Actions

Riboflavin 5′-monophosphate (FMN) acts as a cofactor in flavoproteins and possess biological activity in enzymes?and photoreceptors.

Purification Methods

Purify FMN by paper chromatography using tert-butanol/water, cutting out the main spot and eluting it with water. It can also be purified by adsorption onto an apo-flavodoxin column, followed by elution and freeze drying. It crystallises from aqueous acidic solution. [Mayhew & Strating Eur J Biochem 59 539 1976, Beilstein 26 III/IV 2555.]

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