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60719-84-8

Name Amrinone
CAS 60719-84-8
EINECS(EC#) 262-390-0
Molecular Formula C10H9N3O
MDL Number MFCD00083228
Molecular Weight 187.2
MOL File 60719-84-8.mol

Chemical Properties

Appearance Crystalline Solid
Melting point  294-297°C (dec.)
Boiling point  321.94°C (rough estimate)
density  1.2025 (rough estimate)
refractive index  1.4830 (estimate)
storage temp.  2-8°C
solubility  DMF: 0.3 mg/ml; DMSO: 0.5 mg/ml
form  Crystals
pka 12.05±0.10(Predicted)
color  Crystals from DMF
Water Solubility  Insoluble in water or chloroform. Slightly soluble in acetic acid or DMF. Soluble in DMSO
Usage A selective cAMP phosphodiesterase (PDE-3) inhibitor with positive inotropic and vasodilatory activity. Cardiotonic
CAS DataBase Reference 60719-84-8(CAS DataBase Reference)

Safety Data

Hazard Codes  T,Xn
Risk Statements 
R25:Toxic if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
Safety Statements 
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  DW2500000
HazardClass  6.1(b)
PackingGroup  III
HS Code  2933790002
Toxicity
LD50 orl-rat: 102 mg/kg NDADD8 1,259,83

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