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606-68-8

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Identification

Name
beta-Nicotinamide adenine dinucleotide disodium salt
CAS
606-68-8
Synonyms
NADH
DPNH
NADH2
ENADA
N 8129
NADH 2Na
NADH-NA2
DPNH2-NA2
DPNH, NA2
Co I reduced
Nadide sodium
BETA-NADH 2NA
β-NADH/β-DPNH
NADH (sodium salt)
CoenzyMe I Reduced
CozyMase I Reduced
BETA-NADH DISODIUM
NADH DISODIUM SALT
DPNH DISODIUM SALT
beta-Nicotinamide ad
Codehydrase I Reduced
BETA-NADH DISODIUM SALT
BETA-DPNH DISODIUM SALT
NADH,NADH DISODIUM SALT
Dihydrocodehydrogenase I
DihydrocozyMase DisodiuM
B-NAD, REDUCED, DISODIUM
Codehydrogenase I Reduced
Reduced Codehydrogenase I
B-NAD REDUCED FORM DISODIUM
DIPHOSPHOPYRIDINE NUCLEOTIDE
LB MODIFIED IN BOTTLES 1000ML
BIURET REAGENT WORKING SOLUTION
BETA-NAD REDUCED FORM DISODIUM
N A D H, REDUCED FORM, DISODIUM
Coenzyme I reduced disodium salt
Diphosphopyridine nucleotide reduced
Reduced Diphosphopyridine Nucleotide
Reduced NcotinaMide Adenine Diphosphate
NADH disodiuM salt, trihydrate, reduced
BETE-NICOTINAMIDE ADENINE DINUCLEOTIDE,
BETA-NAD REDUCED FORM DISODIUM, 10 MG PR
HEPES (2-[4-(2-HYDROXYETHYL)-1-PIPERAZIN
Diphosphopyridine nucleotide, reduced form
b-NicotinaMide-adenine Dinucleotide, reduced
beta-NICOTINAMIDE ADENINE DINUCLEOTIDE REDUCED
NICOTINAMIDE ADENINE DINUCLEOTIDE DISODIUM SALT
Hydrate, reduced forM [for BiocheMical Research]
β-Nicotinamide-adenine dinucleotide reduced form
NADH (b-NicotinaMide adenine dinucleotide,reduced
DihydronicotinaMide Adenine Dinucleotide DisodiuM
DIHYDRODIPHOSPHOPYRIDINE NUCLEOTIDE DISODIUM SALT
beta-NicotinaMide adenine dinucleotide disodiuM sa
DIPHOSPHOPYRIDINE NUCLEOTIDE (REDUCED) DISODIUM SALT
DIPHOSPHOPYRIDINE NUCLEOTIDE, REDUCED FORM, DISODIUM
B-NICOTINAMIDE ADENINE DINUCLEOTIDE,*RED UCED FORM D
BETA-NICOTINAMIDE-ADENINE DINUCLEOTIDE, REDUCED, 2NA
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE, DISODIUM SALT
1,4-DihydronicotinaMide Adenine Dinucleotide DisodiuM
eta-d-ribofuranosyl-3-pyridinecarboxamide,disodiumsalt
DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE DISODIUM SALT
DIPHOSPHOPYRIDINE NUCLEOTIDE, REDUCED FORM DISODIUM SALT
NICOTINAMIDE-ADENINE DINUCLEOTIDE (REDUCED) DISODIUM SALT
beta-NicotinaMide Adenine Dinucleotide DisodiuM Salt 
beta-Nicotinamide adenine dinucleotidedisodium salthydrate
B-NICOTINAMIDE ADENINE DINUCLEOTIDE, REDUCED DISODIUM SALT
β-NicotinaMide adenine dinucleotide,disodiuM salt, reduced
BETA-NICOTINAMIDE ADENINE DINUCL. DISO-D IUM SALT RED. HYDR
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE R ED. NA2SALT HYDRAT
β-Nicotinamide adenine dinucleotide, disodium salt, hydrate
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE REDUCED DISODIUM SALT
BETA-DIPHOSPHOPYRIDINE NUCLEOTIDE DISODIUM SALT, REDUCED FORM
B-NICOTINAMIDE ADENINE DINUCL- EOTIDE,REDUCED,DISODIUM (NADH)
b-Nicotinamide adenine dinucleotide reduced form disodium salt
NICOTINAMIDE ADENINE DINUCLEOTIDE (REDUCED FORM) DISODIUM SALT
β-Nicotinamide adenine dinucleotide disodium salt, reduced form
β-Nicotinamide adenine dinucleotide,disodium salt ,98% [reduced]
β-nicotinamide adenine dinucleotide,reduced disodium salt hydrate
β-nicotinamide adenine dinucleotide, reduced disodium salt hydrate
-NICOTINAMIDE ADENINE DINU-CLEOTIDE REDUCED NA2-SALT ANALALYT. GR.
BETA-NICOTINAMIDE ADENINE DINUCLEOTIDE, REDUCED FORM DISODIUM SALT
NICOTINAMIDE ADENINE DINUCLEOTIDE (REDUCED) DISODIUM SALT extrapure
-NICOTINAMIDE ADENINE DINU-CLEOTIDE REDUCED NA2-SALT RESEARCH GRADE
NICOTINAMIDE ADENINE DINUCLEOTIDE >98% (REDUCED FORM) DISODIUM SALT
NICOTINAMIDE-ADENINE DINUCLEOTIDE (REDUCED) DISODIUM SALT(NADH 2Na)
β-Nicotinamide Adenine Dinucleotide Disodium Salt(Reduced Form) 〔NADH
-NicotinaMide adenine dinucleotide,diphosphopyridine nucleotide reduced
β-Nicotinamide adenine dinucleotide, reduced hydrate disodium salt
β-Nicotinamide adenine dinucleotide, disodium salt, hydrate, Reduced Form
b-Nicotinamide adenine dinucleotide phosphate, reduced form, disodium salt
beta-Nicotinamide adenine dinucleotide disodium salt, reduced, trihydrate,98%
Beta-nicotinamide adenine dinucleotide, disodium salt, hydrate, 98%, reduced form
beta-NicotinaMide adenine dinucleotide, disodiuM salt, hydrate, 95+%, reduced forM
beta-Nicotinamide adenine dinucleotide, reduced disodium salt hydrate >=94% (HPLC)
beta-NicotinaMide adenine dinucleotide, disodiuM salt, hydrate, reduced forM, 98% 1GR
Nicotinamide adenine dinucleotide >98% (reduced form) disodium salt nutraceutical grade
β-NicotinaMide Adenine Dinucleotide DisodiuM Salt Hydrate, reduced forM [for BiocheMical Research]
beta-NicotinaMide Adenine Dinucleotide DisodiuM Salt Hydrate, reduced forM [for BiocheMical Research]
Adenosine 5'-(Trihydrogen diphosphate) P'→5'-ester 1,4-Dihydro- 1-β-D-ribofuranosylnicotinaMide SodiuM Salt
1-[5-O-[(5'-Adenylyloxy)(sodiooxy)phosphinyl]-β-D-ribofuranosyl]-1,4-dihydro-3-pyridinecarboxamide sodium salt
β-DPNH, β-NADH, Coenzyme I reduced disodium salt, Diphosphopyridine nucleotide reduced disodium salt
Adenosine 5-(trihydrogen diphosphate), P?5-ester with 1,4-dihydro-1-.beta.-D-ribofuranosyl-3-pyridinecarboxamide, disodium salt
Coenzyme I Disodium Salt Cozymase Disodium Salt beta-Diphosphopyridine Nucleotide Disodium Salt beta-DPNH Disodium Salt beta-NADH Disodium Salt
β-Nicotinamide adenine dinucleotide, reduced disodium salt,β-DPNH, β-NADH, CoenzymeI reduced disodium salt, Diphosphopyridine nucleotide reduced disodium salt
eta-d-ribofuranosyl-3-pyridinecarboxamide, disodium salt beta-nicotinamide adenine dinucleotide, disodium salt, hydrate beta-nicotinamide adenine dinucleotide disodium salt,trihydrate
Disodium 1-[(2R,3R,4R,5R)-5-[[[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-oxido-phosphoryl]oxy-oxido-phosphoryl]oxymethyl]-3,4-dihydroxy-oxolan-2-yl]pyridine-5-carboxamide
β-Nicotinamide adenine dinucleotide, reduced disodium salt β-DPNH Coenzyme I reduced disodium salt Diphosphopyridine nucleotide reduced disodium salt β-Nicotinamide adenine dinucleotide, disodium salt, hydrate β-NADH disodium salt
EINECS(EC#)
210-123-3
Molecular Formula
C21H27N7Na2O14P2
MDL Number
MFCD00036200
MOL File
606-68-8.mol
Molecular Weight
709.4

Chemical Properties

Definition
A dehydrogenase complex that is the reduced formof NAD.
Appearance
beige powder
Melting point 
140-142°C
storage temp. 
2-8°C

solubility 
H2O: 50 mg/mL, clear to nearly clear, yellow

form 
Powder
color 
Yellow
Stability:
Stable. Incompatible with strong oxidizing agents.
PH
7.5 (100mg/mL in water, ±0.5)
Water Solubility 
soluble
BRN 
5230241
InChIKey
QRGNQKGQENGQSE-WUEGHLCSSA-L
CAS DataBase Reference
606-68-8
EPA Substance Registry System
Adenosine 5'-(trihydrogen diphosphate), P'.fwdarw.5'-ester with 1,4-dihydro-1-.beta.-D-ribofuranosyl- 3-pyridinecarboxamide, disodium salt(606-68-8)

Hazard Information

Chemical Properties
beige powder
Uses
One of the biologically active forms of nicotinic acid. Serves as a coenzyme of hydrogenases and dehydrogenases. NAD usually acts as a hydrogen acceptor, forming NADH which then serves as a hydrogen d onor in the respiratory chain. Present in living cells primarily in the reduced form (NADPH) and is involved in synthetic reactions. Occurs in 2 forms, α-NAD and β-NAD, distinguished by the configura tion of the ribosyl nicotinamide linkage. Only the β-anomer is bioactive.
Purification Methods
This coenzyme is available in high purity, and it is advisable to buy a fresh preparation rather than to purify an old sample as purification will invariably lead to a more impure sample contaminated with the oxidised form (NAD). It has UV max at 340nm ( 6,200 M-1cm-1) at which wavelength the oxidised form NAD has no absorption. At 340nm a 0.161mM solution in a 1cm (pathlength) cell has an absorbance of 1.0 unit. The purity is best checked by the ratio A280nm/A340nm ~2.1, a value which increases as oxidation proceeds. The dry powder is stable indefinitely at -20o. Solutions in aqueous buffers at pH ~7 are stable for extended periods at -20o and for at least 8hours at 0o, but are oxidised more rapidly at 4o in a cold room (e.g. almost completely oxidised overnight at 4o). [UV: Drabkin J Biol Chem 175 563 1945, Fluorescence: Boyer & Thorell Acta Chem Scand 10 447 1956, Redox: Rodkey J Biol Chem 234 188 1959, Schlenk in The Enzymes 2 250, 268 1951, Kaplan in The Enzymes 3 105, 112 1960.] Deuterated NADH, i.e. NADD, has been purified through the anion exchange resin AG-1 x 8 (100-200 mesh, formate form) and through a Bio-Gel P-2 column. [Viola et al. Anal Biochem 96 334 1979, Beilstein 26 III/IV 3639.]

Safety Data

Hazard Codes 
Xn
Risk Statements 
23/24/25-36/37/38-39/23/24/25-40-22
Safety Statements 
26-36/37/39-45-24/25-36/37
WGK Germany 
3


3-10-23
TSCA 
Yes
HS Code 
29349990

Material Safety Data Sheet(MSDS)

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