ChemicalBook CAS DataBase List 57808-65-8

57808-65-8

Name	Closantel
CAS	57808-65-8
EINECS(EC#)	260-967-1
Molecular Formula	C22H14Cl2I2N2O2
MDL Number	MFCD00661151
Molecular Weight	663.07
MOL File	57808-65-8.mol

Synonyms

5'-CHLORO-4'-(4-CHLORO-ALPHA-CYANOBENZYL)-3,5-DIIODO-2'-METHYLSALICYLANILIDE CLOSANTEL CLOSANTEL BASE N-[5-CHLORO-4-(4-CHLORO-ALPHA-CYANOBENZYL)-2-METHYLPHENYL]-2-HYDROXY-3,5-DIIODOBENZAMIDE n-[5-chloro-4-[(chlorophenyl)cyannomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodobenzamid 5-diiodo-y- benzamide,n-(5-chloro-4-((4-chlorophenyl)cyanomethyl)-2-methylphenyl)-2-hydrox faskoverm iodobenzamide n-(5-chloro-4-((4-chlorophenyl)cyanomethyl)-2-methylphenyl)-2-hydroxy-3,5-di Closantelfreebase N-[5-CHLORO-4(4-CHLOROPHENYL)CYANOMETHYL]-2-METHYLPHENYL]-2-HYDROXYL-3,5-DIIODO BENZAMIDE Benzamide, N-5-chloro-4-(4-chlorophenyl)cyanomethyl-2-methylphenyl-2-hydroxy-3,5-diiodo- 5'-chloro-4'-(4-chloro-α-cyanobenzyl)-3,5-diiodo-2'-methylsalicylanilide CLOSANTEL(PATENT) N-[5-CHLORO-4(4-CHLOROPHENYL)CYANOMETHYL]-2-METHYLPHENYL]-2-HYDROXYL-3,5-DIIODOBENZAMIDE(CLOSANTEL) N-[5-Chloro-4-[(chlorophenyl)cyannomethyl]-2-methylphenyl]-2-hydroxy-3,5-diiodobenzamide N-[5-Chloro-4-(4-chloro-α-cyanobenzyl)-2-methylphenyl]-2-hydroxy-3,5-diiodobenzamide, 5μ-Chloro-4μ-(4-chloro-α-cyanobenzyl)-3,5-diiodo-2μ-methylsalicylanilide Diantel N-(5-Chloro-4-((4-chlorophenyl)cyanomethyl)-2-methylphenyl)-2-hydroxy-3,5-diiodobenzamide

Chemical Properties

Melting point	217.8°
Boiling point	590.5±50.0 °C(Predicted)
density	1.8759 (estimate)
storage temp.	0-6°C
solubility	DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.16 mg/ml
form	neat
pka	5.99±0.48(Predicted)
color	White to off-white
CAS DataBase Reference	57808-65-8(CAS DataBase Reference)

Safety Data

Hazard Codes	Xn
Risk Statements	R22:Harmful if swallowed. less more
RIDADR	2811
WGK Germany	3
RTECS	CV2444250
HazardClass	6.1(b)
PackingGroup	III
Toxicity	A veterinary drug for the treatment of fluke and nematode infestations. In 1993, some was included in a batch of donated drugs sent to Lithuania. Attempts to match the product with the names of other medicines on accompanying literature resulted in its misidentification as a treatment for endometriosis. Eleven women lost their eyesight; though this has since returned, they were left with eye pain and are unable to work. less more

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